Sore muscles after workouts? Could be AMPD1 deficiency. (Patrons only)

AMPD1 DeficiencyDo you end up getting sore after every work out at the gym? It could be that a deficiency caused by the AMPD1 genetic variant is adding to your soreness. (Or it could be that you are working out too hard :-)

Adenosine Monophosphate deaminase is an enzyme coded for by the gene AMPD1 and acts in the skeletal muscles to convert AMP to IMP. There is one common polymorphism, C34T, that causes a decrease in function of this enzyme. Caucasians and Africans carry the variant at a frequency of about 10% (heterozygous).

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