FTO and m6A Methylation
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
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Building Up Iron: Hemochromatosis mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
Elevated Fibrinogen: Risk factor for blood clots
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
BPIFB4 Gene: Linked to Longevity and Heart Health
Discover the impact of the BPIFB4 gene on longevity and immunity, and find out if you have the longevity variant in your genotype report.
Vitamin K: Bone Strength, Blood Clots, Calcification, and Genetics
Genetic variations cause people to have higher or lower levels of vitamin K, which can affect blood clotting. Learn more about the genes that affect vitamin K and how it relates to your genetic raw data.
Vitamin B6: Genetics, Absorption, and Deficiency
Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.
Coronary Artery Disease: Genetic Susceptibility to Heart Disease
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
Gilbert’s Syndrome: A Genetic Disorder Causing High Bilirubin
Gilbert’s syndrome is an inherited condition where the body doesn’t break down bilirubin efficiently. Discover the benefits of higher bilirubin levels in this syndrome and some possible risks.
NLRP3: Genetics Variants that Increase Chronic Inflammation
What makes people more susceptible to chronic inflammatory diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
Histamine Intolerance: Genetic Report, Supplements, and Real Solutions
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
BH4: Tetrahydrobiopterin Synthesis, Recycling, and Genetic SNPs
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
Alzheimer’s Gene: Find your APOE type from your genetic raw data
The APOE gene variants are linked with the risk of Alzheimer’s disease. Find out whether you carry the APOE risk type for Alzheimer’s – and learn what research shows about supplements and lifestyle changes to prevent this disease.
Homocysteine: Genetics, High Homocysteine Levels, and Solutions
High homocysteine levels are strongly linked to an increased relative risk of cardiovascular diseases. Find out how your genes impact homocysteine levels.
MTHFR Mutation: What is it? How to check your raw data.
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.
Lipoprotein(a): Genetics and Lp(a) Levels
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).
Niacin and Heart Disease: Genetic Interaction
Higher intake of niacin, along with certain genetic variants, has been shown to increase the risk of heart disease. Check your SNPs here.
Taurine: Research on Healthspan and Supplements
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine.
CoQ10: Genes, Benefits, and Mitochondrial Energy
CoQ10, or ubiquinone, is an integral part of mitochondrial energy production. It is also used as a lipid-soluble antioxidant. Learn how age and genes affect it.
Nattokinase and Lumbrokinase: Natural Supplements for Clots
Two natural fibrinolytics to reduce clotting are nattokinase and lumbrokinase. Learn more about these options based upon the newest research and clinical trials.
TNF-alpha: Inflammation, Chronic Diseases, and Genetic Susceptibility
Discover the role of TNF-alpha in inflammation and its link to chronic diseases. Learn how genetic variants affect TNF-alpha levels and explore natural solutions for chronic inflammation.
Blood Pressure, MTHFR, and Riboflavin
The common MTHFR C677T variant increases the relative risk of high blood pressure. Learn how to add more Riboflavin (B2) into your diet to reduce risk.
Estrogen, Histamine, and Mast Cell Connections
Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.
Sudden Cardiac Death and Hypertrophic Cardiomyopathy
Genetic mutations that cause hypertrophic cardiomyopathy can increase the risk of sudden cardiac death.
ADRA1A Receptors: Blood Vessel Reactions Under Stress
We have many systems in place to control blood pressure and heart rate. The ADRA1A receptors are part of this system. Discover how variants can influence blood vessel stress response and how others are connected to cognitive changes.