BPIFB4 Gene: Linked to Longevity and Heart Health
Discover the impact of the BPIFB4 gene on longevity and immunity, and find out if you have the longevity variant in your genotype report.
heart
TNF-alpha: Inflammation, Chronic Diseases, and Genetic Susceptibility
Discover the role of TNF-alpha in inflammation and its link to chronic diseases. Learn how genetic variants affect TNF-alpha levels and explore natural solutions for chronic inflammation.
HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
Blood pressure, MTHFR, and riboflavin
The common MTHFR C677T variant increases the relative risk of high blood pressure. Learn how to add more Riboflavin (B2) into your diet to reduce risk.
Estrogen, histamine, and mast cell connections
Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.
Sudden Cardiac Death and Hypertrophic Cardiomyopathy
Genetic mutations that cause hypertrophic cardiomyopathy can increase the risk of sudden cardiac death.
MTHFR Mutation: What is it? How to check your raw data.
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.
ADRA1A Receptors: Blood vessel reactions under stress
We have many systems in place to control blood pressure and heart rate. The ADRA1A receptors are part of this system. Discover how variants can influence blood vessel stress response and how others are connected to cognitive changes.
Magnesium deficiency? Genes that Impact Magnesium Levels
Are your magnesium levels low? Understanding your genes can help you decide whether you may need more magnesium in your diet or via supplements.
Gilbert’s Syndrome: A genetic disorder causing high bilirubin
Gilbert’s syndrome is an inherited condition where the body doesn’t break down bilirubin efficiently. Discover the benefits of higher bilirubin levels in this syndrome and some possible risks.
Long Spike
Discover the research and genetic links to why you may be more susceptible to certain outcomes with long spike.
IL13 Genomics: Elevating Th2 Immune Response
Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you toward a Th2-dominant immune response, and variants increase the risk of allergies and asthma.
TTR gene: hereditary transthyretin amyloidosis and ATTR CM
New research shows that hereditary transthyretin amyloidosis (hATTR) may be more common, especially in people of African ancestry. Understand your genetic risk before irreversible damage.
Small Fiber Neuropathy: Genetics, Causes, and Possible Solutions
Small Fiber Neuropathy (SFN) results in burning pain, numbness, odd sensations, or autonomic nervous system issues. Learn more about the possible causes and potential solutions to this debilitating disorder.
7 genetic variants that increase your risk of blood clots
Some people are unique in their ability to form clots more easily. This article covers six different genes and the seven genetic variants that increase the risk of blood clots. It is a timely topic because blood clots seem to be a severe complication for people with COVID-19.
Spike Protein, Mast Cells, Histamine, and Heart Rhythms
Do you know of someone with unexplained heart palpitations, spiking blood pressure, dizziness, and tinnitus? Discover how research is linking these symptoms to histamine, mast cells, and the spike protein.
Lipoprotein a: How to check your genetic data for Lp(a)
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).
Nattokinase and Lumbrokinase: Natural supplements for clots
Two natural fibrinolytics to reduce clotting are nattokinase and lumbrokinase. Learn more about these options based upon the newest research and clinical trials.
Von Willebrand Factor Deficiency
von Willebrand disease is a bleeding disorder in which blood doesn’t clot properly. Discover how genetic mutations cause the von Willebrand factor not to perform as it should.
What is YOUR risk of heart disease?
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
LDL Cholesterol Genes
Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.
FTO and m6A methylation: From COVID to Cancer to Obesity
The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Elevated Fibrinogen: Risk factor for blood clots
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
NLRP3 Inflammasome, Genetics, and Chronic Inflammation
What makes people more susceptible to chronic inflammatory diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
Histamine Intolerance: Understanding Your Genetics and Managing Symptoms
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Rapamycin, mTOR, and Your Genes
Rapamycin is an antibiotic used as an immunosuppressant, an anti-cancer agent, and to prevent blocked arteries. Rapamycin is now the focus of longevity and healthspan-extending research by inhibiting mTOR.