Snips about SNPs: Evening chronotypes

The aptly named CLOCK gene is part of your core circadian rhythm. Recently, researchers have linked the circadian clock to a variety of different chronic conditions including obesity, heart disease, diabetes, and depression.

Your CLOCK gene variant may impact whether you are more likely to be active during the evening and stay up a little later.

Check your 23andMe results for rs1801260 (v.4 and v.5):

  • G/G: higher activity in the evening, possible delayed sleep onset, increased risk for obesity[ref][ref][ref]
  • A/G: somewhere in between
  • A/A: normal

Want more details? Check out the full article on circadian genes.

*SNP stands for Single Nucleotide Polymorphism, which is when one of the nucleotide bases (the A, C, G, or Ts) is replaced by a different nucleotide base in a gene.  Want to know more about your genes? Read through all the Snips about SNPs



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