What to do with your 23andMe raw data

You’ve spit in the little tube, mailed it off to 23andMe, and finally have your results available. Yay!  After playing around with all the fun ancestry information on 23andMe, you should download your data and dig into finding out more about yourself.

Seriously, the data is yours and you really should go download the raw data file and keep it safe.

Here are a few places to get you started on your quest to find out more about your genetics:

1. This blog!  There is a ton of information here, and it is all free.  Click the links in each article to access your 23andMe results.

2. Promethease and codegen.eu:  These are reports that you can run on your 23andMe results which compare your SNPs with those listed in www.snpedia.com.  These both can point to issues for which you may be genetically susceptible.  It is a good starting point to let you know what to look into, but it can also be overwhelming to know which information is truly important.

The Promethease report is $5 and gives a nicely formatted report that is easy to navigate.  The Codegen.eu report is free and has similar information to Promethease, based on snpedia.com along with links to other information.

3. Read, Read Read!  There are a lot of blogs and groups giving tons of suggestions and protocols for certain polymorphisms.  They may be a good starting point for your research, but you should always look into where the author is getting their information.  Don’t just blindly follow what someone says on “the Facebook”!

Genetics can truly be the key to optimizing your health, and it is worthwhile to spend the time reading and understanding the research.  Nope, it isn’t easy.  Just keep digging and googling the words that you don’t know!

SNPedia.com is a good starting point.  It is a user-edited resource with links to research papers on genetic variants.  Pubmed.gov is the NIH searchable database for medical research studies.

4. Methylation Pathway Analysis:  This report gives a lot of background information on methylation cycle issues.  It is based on the work of Dr. Amy Yasko, who is an expert in molecular biology and has written several books on autism.  Dr. Yasko’s website has a wealth of information on genetics and methylation.  She has shared much of her research openly and has one of her books available on her website to read for free.

5.  Paid websites that may or may not be worth the money (I actually haven’t tried most of them…):

  • StrateGene – $45.  Gives you a report of what your polymorphisms are for methylation pathways.  They recommend working with a physician to interpret the report.
  • LiveWello – $19.99  When you upload your 23andMe data, you can see the major and minor alleles for a bunch of SNPs.  There is a community of people who are interested in talking about their genes, and there are links to practitioners who you can hire.
  • Nutrahacker – from $37 – $85.  This website has several reports that you can buy on celiac, methylation, and carrier status.  (Most of the information is actually available on this blog and other blogs for free, but if money is not an issue, the reports are a way to get the information in a nice, printable format.)

If you have suggestions for other websites, please add them in the comments below.

updated 10/2017

Comments 27

  • Hello, Сan you add option of using the service ch3enko.com , if you would appreciate its capabilities and ease of use of the information. Thank you.

  • Check out http://www.infino.me

    I’ve built a interpretation engine that links to thousands of scientific articles. We’re completely free and nonprofit.

  • Professional and advanced interpretation engine for nutrigenetics and sports genetics – https://dnalifestylecoach.com

    P.S. Ping me for a free access.

  • Get some extra mileage out of your 23andMe data. DNA Romance is online dating based on your SNPs, see http://www.dnaromance.com

  • You should look into http://www.impute.me – it really seems to be the most advanced out there

    • Thanks for the recommendation of this website. Looks very interesting — but I worry about the security of my genetic information. This may be a website to come back to in the future when they have all the kinks worked out and a more legit looking privacy policy. I applaud the concept and hope that the devloper / geneticists can raise enough through their kickstarter to put together a secure site.

      • What’s the worry actually? It seems it’s one of the only sites that don’t store the genetic information (after 2 weeks it says). And definetly the only open-source option, so you can audit yourself

  • Is there a site you can take your dna and your partner’s and get a probability of traits of your child?

  • foundmyfitness.com has a free analysis tool for 23andme data. The philosophy with their limited reporting is to only report on concerns that you can mitigate with diet, lifestyle and/or supplementation. My only criticism is some ‘biggies’ like MTHFR are not in the report (as far as I am aware).

  • Single? Chemistry is important, RIGHT?
    Get some help from DNA Romance, it’s matchmaking based on science and it’s free to try http://www.dnaromance.com
    Now accepting raw DNA data from Ancestry.com, 23andMe, ftDNA, MyHeritage,……with many more file formats to come

  • http://www.toolboxgenomics.com

    We provide dietary and lifestyle recommendations based on your 23andMe and soon to be Ancestry.com data. We have manually combed through over 10,000 published research articles to bring users only best quality research out there!

  • Hi! Can you please list service from Xcode Life Sciences? They have very firm policies on client data confidentiality. Please do go through the page “https://www.xcode.in/23andme-raw-data-upload” for information on the traits and panels they cover.

  • Is the “Ancestry Only” data useful at all (under the new v.5) for getting health data from these other avenues? Or do you have to buy the full kit from 23&me to get useful results?

    • I think the Ancestry Only data is still useful from the new v.5 format. I think about 2/3 of what I cover in my blog posts is covered on the new chip, and I’m in the process of (slowly) going back through and indicating which version (v.4 and/or v.5) each blog post covers. And going forward, I’m going to be covering some SNPs that are only available on the v.5 chip.
      Hope this helps!
      Debbie

  • So would I basically get the same info with my raw data from 23andme’s ancestry only kit if I just input that into one of the suggested services above? And save $150?

    • The raw data file is the same from 23andMe whether you order the Ancestry only option or the Health and Ancestry option. You can upload that raw data file to a variety of different places (some free, some that cost $), and get various different health reports. None of these are exactly the same health information that 23andMe offers. But pretty much all of the health reports from anywhere are based on scientific studies that are publically available. You can use the raw data yourself through reading through journal articles on the topics that you are interested in. http://www.snpedia.com is another great website to use if you are searching for specific health topics.
      Lots of options for you!
      Debbie

  • Promethease is $10.

  • Thanks for all the valuable information on this website. I’ve been a doctor for 35 years and have been into genetic medicine for five and am appalled that most doctors are still ignoring this information and leaving patients struggling to find answers – which are often the wrong answers.

    I wrote a book which reviews the importance of genetic health reports and many of the companies offering this service: how many genes they test, the nature of the report (nutrition only, selling supplements, etc) and price. It’s free as an ebook on Amazon and is called Genetic Health Reports. I’m not trying to hock my book but get this information out to the medical community and public.
    Best, Tom Ballard, RN, ND

    • Thanks so much for adding your book information here. I’ve had several people ask for book recommendations and hadn’t had a good resource to recommend. I’m off to Amazon to download your book!
      Debbie

      • Great. I hope you find my book helpful. I have another one coming out later this year. I’ll let you know when it’s ready.
        Also, If you’re looking at other genetic report services, consider including mine, http://www.NaturalDNASolutions.com. It is more expensive than most ($149) but it’s also much more comprehensive and was developed to save doctors and patients hours of research. What I found was that patients are spending many hours researching their DNA, learning genetics, trying to figure out solutions for their health problems. To address this I founded Natural DNA Solutions (NDS) four years ago. It’s unique in that each genetic health report is individualized. It looks at 1400 genes using data from 23andme or Ancestry.com. It begins with a genetics 101 section, then describes the function of the genes in question, lists the possible health consequences of gene variations (SNPs), and then focuses on the genes that are the most likely problem for the patient. Most importantly, the report includes treatment options – nutrition, supplements, detoxification, and activities such as meditation, exercise, stress reduction. NDS reports are usually 120-150 pages long. So, while the price is higher, it saves hours of research and includes valuable treatments based on my 35 years in practice. Also, if you’re interested in selling NDS report services, I we can discuss discount pricing for you. Meanwhile, thanks again for this fine site and spreading the word about genetic medicine. Best, Tom

        • Hi Tom,
          I just downloaded your book, too and am looking forward to reading it (and getting my genetic data in February!). Do you interpret data from Genes for Good?

          • Hi Alissa,
            No, sorry, I can only process the data from 23andme or Ancestry.com, both of which have large raw data bases. Genes for Good is for research purposes.

            Hope this helps,
            Tom

  • I recommend http://www.xcode.in. It is moderately priced and delivers customize-able genetic health reports within 24 hours. I have found the information gleaned there to be integral to my diet, supplementation, and exercise routine and I think it would be beneficial for so many people to do. Well worth it!

    Laurel Jimenez, USA

  • Is there a website that takes the raw data from 23andMe and gives diet and exercise tips based on DNA?

    • Hi Jeanette,
      There are several places that will run their own DNA tests and give you reports on either diet or exercise. DNA fit is one, but I haven’t used it myself to recommend it.
      I’m actually working now on a ‘report’ format that will take your 23andMe data and consolidate it with all the diet research studies that I have articles about on this site already.

      The hard part of recommending some of the reports that I’ve seen other sites produce about diet or exercise is that the research really isn’t as specific as the reports make it seem. There isn’t a lot of research that says, for example, “if you have SNPs A, B, and C you should eat these foods”. The research is more along the lines of “if you have this certain SNP and are of this specific population, then saturated fat in the top quartile of consumption will raise your risk of heart disease by a small amount.” This doesn’t make for a cut and dried recommendation to cut out all saturated fats, but is more of a ‘heads up’ to keep an eye on it if test results are indicating heart disease risk factors.

      This is turning into a long-winded explanation of my frustration with other sites that over-hype a lot the genetic studies, coupled with my own struggles to create a report format that distills down a huge amount of information into something readable, but still with real information.

      Thanks for reading and commenting!
      Debbie

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