Autophagy Genes

Autophagy is a general term for cellular pathways that move something from the cytoplasm of the cell into the lysosome for degradation. The term comes from the Greek 'auto' (self) and '-phagy' (to eat).  So when you see articles touting 'autophagy diets' as the latest and greatest for longevity or beautiful skin, realize that the term is just a general one that applies to a cellular process that goes on all the time in our cells. Let me see if I can explain a bit of the biology behind this, and then I’ll go into how your genes play a role in autophagy. Back to high school science class:  Inside almost every cell in the body is an organelle called a lysosome. It is made up of a membrane that surrounds a bunch of different enzymes for breaking down proteins.  This is a way our cells can clean up after themselves, and also how they get rid of foreign invaders like bacteria. (more…)

By Debbie Moon, ago