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Estrogen, histamine, and mast cell connections

Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.

Glucuronidation: UGT genetic variants, detoxification, and hormone balance

The UGT family of enzymes is responsible for an important part of phase II detoxification. This article explains what the UGT enzymes do in the body, how your genes impact this part of detoxification, and lifestyle factors that can increase or decrease this detox process.