GSTM1: GST enzymes and glutathione for environmental toxins

Exposure to many different man-made chemical compounds occurs every day, and our exposure to new toxicants exceeds what our ancestors experienced. Several common GST variants decrease the function of the GST enzymes.

Nrf2 Pathway: Increasing the body’s ability to get rid of toxins

The Nrf2 (Nuclear factor erythroid 2–related factor) signaling pathway regulates the expression of antioxidants and phase II detoxification enzymes. It is a fundamental pathway important in how well your body functions. Your genetic variants in the NFE2L2 gene impact this NRF2 pathway.