News and Research: Gut microbiome changes in aging
Study: Gut microbiome pattern reflects healthy ageing and predicts survival in humans Nature Metabolism, Feb 2021 Overview: This large study …
News and Research
Below is a roundup of recent research studies of interest.
Want to let me know about an interesting study? I would love to hear from you.
News and Research: MOTS-c as an exercise mimetic
Study: MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis Nature communications, January 2021 Overview: A …
News and Research: MTHFR and dietary folate
Study: Food Intervention with Folate Reduces TNF-α and Interleukin Levels in Overweight and Obese Women with the MTHFR C677T Polymorphism: …
News and Research: Microdose lithium for COVID-19 and cellular senescence in astrocytes
Title: Microdose lithium reduces cellular senescence in human astrocytes – a potential pharmacotherapy for COVID-19? Journal on Aging, June 2020 …
News and Research: Restoring metabolism to brain cells to reverse cognitive decline
Study: Restoring metabolism of myeloid cells reverses cognitive decline in ageing (Nature, January 2021) Overview: This fascinating animal study investigates …
Genome-wide study looking at suicide deaths
Study title: Genome-Wide Association Study of Suicide Death and Polygenic Prediction of Clinical Antecedents The American Journal of Psychiatry, Nov. …
News and Research: Resilience of the gut microbiome
Title: Long-term dietary intervention reveals resilience of the gut microbiota despite changes in diet and weight American Journal of Clinical …
News and Research: Hyperbaric oxygen increases telomere length
Research from Tel Aviv University shows that hyperbaric oxygen (high-pressure oxygen exposure in a pressurized chamber) increases telomere length in T-cells, which is a sign of decreasing aging.
News and Research: A PCSK9 mutation that protects against disease
Canadian researchers have discovered that a rare genetic variant in the PCSK9 gene increases longevity through decrease heart disease and liver injury.
News and Research: Melatonin supplementation reduces COVID-19 susceptibility
Study Title: A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19 …
News and Research: Core circadian clock function vital for regenerating insulin producing cells
Study title: The core clock transcription factor BMAL1 drives circadian β-cell proliferation during compensatory regeneration of the endocrine pancreas Journal …
News and Research: Average home lighting in the evening decreases melatonin and hurts sleep quality
Study title: Evening home lighting adversely impacts the circadian system and sleep Nature, Nov 2020 Overview of the study: Quick …
News and Research: Microdose lithium formulation and Alzheimer’s prevention
Study Title: NP03, a Microdose Lithium Formulation, Blunts Early Amyloid Post-Plaque Neuropathology in McGill-R-Thy1-APP Alzheimer-Like Transgenic Rats Journal of Alzheimer’s …
News and Research: Mother’s can pass allergens to babies
Study title: Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE Science, Oct 29, 2020 Overview: This interesting …
News and Research: Aspirin and COVID-19
Title: Aspirin Use is Associated with Decreased Mechanical Ventilation, ICU Admission, and In-Hospital Mortality in Hospitalized Patients with COVID-19 Journal …
News and Research: MRI & PET scans on brains of COVID patients who lost their sense of smell
Title: Structural and metabolic brain abnormalities in COVID-19 patients with sudden loss of smell PREPRINT Oct. 18, 2020 Overview of …