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Nicotinamide Riboside and NMN: Boosting NAD+ in Aging

Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.

Shilajit: Muscles, bones, and testosterone

Shilajit is a supplement that contains fulvic acid, metabolites, and minerals. It has been used for centuries in Ayurvedic medicine, and clinical trials show it has positive benefits for osteoporosis, testosterone, male infertility, and muscle recovery.

Chronic Lyme: Genetic Susceptibility

The interesting thing about Lyme disease is that the genetic variants you carry impact both how the disease affects you and how well antibiotics work for you. Learn whether your genetic variants are linked to post-treatment Lyme disease symptoms such as joint pain. (Member’s article)

Maca Root: Research-backed Benefits and How It Works

Explore the benefits of Maca root, a cruciferous vegetable with adaptogenic properties, known for balancing hormone levels and aiding menopausal symptoms. Learn about its potential side effects, gene interactions, and the science behind its unique bioactive compounds.

Essential Tremor: Causes and Possible Solutions

Essential tremor (ET) is a neurological disease causing involuntary shaking in places of the body while performing tasks such as writing or eating. Learn more about this disease and discover the genetic causes of ET.

Creatine: Boosting Muscles and Increasing Brain Power

Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.

image showing power lifters who were likely to have the ACTN3 functional polymorphism

ACTN3 Gene: Deficiency and Muscle Type

The ACTN3 gene codes for actinin alpha-3, a protein found in fast-twitch muscles. Some people don’t produce this protein, which changes the composition of their muscles. Elite athletes may be limited by this genetic change.

Tendinitis Genes

Do you have problems with your tennis elbow, rotator cuff, knees, or Achilles tendon? Discover how your genes influence the risk of having tendon problems.

Growing up ‘big boned’: MC4R gene and obesity

There are several key players in our body’s regulation of hunger, satiety, and energy expenditure. Leptin and ghrelin are two pivotal hormones involved in our desire to eat. Within that leptin pathway, another key regulator of our body weight is MC4R. (Member’s article)

Inclusion Body Myositis: Genomics and Solutions

Inclusion body myositis is a progressive, chronic condition that causes muscle weakness. It may be an interplay between inflammation, the dysregulation of proteins, mitochondrial dysfunction, and changes to autophagy. Somewhere in the mix, autoimmunity may be triggering it.

PPAR-Delta: Burning off the Fat

PPARδ is a key player in how and when your muscles burn fat for fuel. Genetic variants in the PPARD gene impact how well your muscles utilize fatty acids. These variants also impact how much of a fat-burning benefit you get from exercise.

Will statins give you muscle pain?

Statins are one of the most prescribed medications in the world. One side effect of statins is myopathy, or muscle pain and weakness. Your genetic variants are significant in whether you are likely to have side effects from statins.

Athletic Performance Genes

Genes control the formation, composition, and type of muscle fiber. Learn how to optimize your training when genetics comes into play, affecting muscle composition and endurance.

Should you eat organic? Detoxifying Organophosphates

Is buying organic worth the extra cost? There isn’t a one-size-fits-all answer to that question. Pesticides that are sprayed on conventionally grown foods affect people differently. Some people carry genetic variants that decrease their ability to detoxify specific pesticides, others may be more resilient. This is Part Two in a multipart series on pesticide detoxification.