GLP-1 Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response
Genes affect how well semaglutide (Ozempic) and tirzepatide work. Check your GLP-1 receptor gene variants linked to weight loss response. Genotype report included.
circadian rhythm
ME/CFS and Genetics: Chronic Fatigue Syndrome Genes, Immune Pathways, and Natural Solutions
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
Histamine Intolerance Genetics: DAO & HNMT Genes, Supplements
Genetic variants in DAO and HNMT genes affect histamine breakdown. Check your AOC1, HNMT, and HDC genotype. Low-histamine diet, DAO supplements, and more.
Nicotinamide Riboside and NMN: Boosting NAD+ in Aging with Supplements
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Lithium Orotate and Vitamin B12: Benefits for Mood and Cognitive Support
For some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12. But other people may have little to no response. The difference may be in your genes.
Circadian Rhythm Disruption as a Root Cause of Depression
Circadian clock gene variants in CLOCK, BMAL1, PER, CRY, NPAS2, and OPN4 interact with light exposure to disrupt hormones, sleep, and mood, increasing risk for depression, anxiety, and seasonal affective disorder.
Specialized Pro-resolving Mediators (SPMs): The Resolution of Inflammation
The resolution of inflammation is an active process that depends on lipid mediators, called specialized pro-resolving mediators (SPMs).
Your APOE Type and Alzheimer’s Risk: How to Find It, What It Means, and What to Do
Find out your APOE type, understand your Alzheimer’s risk by genotype, sex, and ancestry, and learn about real prevention strategies.
Problems sleeping? Your genes can point to individualized solutions
Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
FTO and m6A Methylation: Heart Health, Obesity, and Genetics
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Genetic Mutations that Protect Against Alzheimer’s Disease
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
Migraine Solutions Tailored to Your Genes: Triggers, Treatments, and Tools
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Fatty Liver Disease: Genetics and Reasons for NAFLD, MASLD
Non-alcoholic fatty liver disease (NAFLD) can be caused by genetic susceptibility, diet, and lifestyle factors. The good news is that fatty liver disease is reversible.
How to Shift Your iPhone Screen to Red at Night
Learn how to shift your iphone screen to be completely red at night (no blue light) with a triple-click of the power button.
HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
ADHD: Causes, Neurochemistry, and How to Check Your Genetic Raw Data
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
Parkinson’s Disease Risk: Genetics, Environmental Exposures, and Prevention Strategies
Parkinson’s: Explore key genes, environmental risks, gut microbiome factors, and research‑based lifehacks that may help protect dopaminergic neurons.
Brain Fog: Causes, genetics, and individualized solutions
Brain fog has many roots: nutrient deficiencies, hypoxia, inflammation, viral infections, microclots, histamine, amino acid metabolism, and genetics — plus targeted strategies to restore clear thinking.
Dopamine Synthesis SNPs: Genes, lifestyle, diet, and dopamine optimization
Genetic variants in dopamine synthesis and breakdown genes interact with circadian rhythm, gut microbes, nutrients, and toxins, shaping risks for procrastination, psychosis, hypertension, Parkinson’s, and addiction.
MC4R: Leptin, Melanin, Genes and Weight Gain
There are several key players in our body’s regulation of hunger, satiety, and energy expenditure. Leptin and ghrelin are two pivotal hormones involved in our desire to eat. Within that leptin pathway, another key regulator of our body weight is MC4R. (Member’s article)
Vitamin D Genes
Your vitamin D levels are impacted by sun exposure and your genes. Learn more about how vitamin D is made in the body and how your genetic variants impact your levels.
Melanopsin: Light response, Circadian Rhythm, and Blue Light Exposure
Melanopsin is the receptor for blue light. It is found in the retina, skin, adipose tissue, and blood vessels. Genetic variants can impact reaction to blue light.
Leaky Gut Genes: Emulsifiers in Processed Foods
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Chronic Inflammation: Causes and Natural Solutions
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Restless Leg Syndrome and Periodic Limb Movement Disorder (PLMD): Genes and Solutions
Many know the frustration of disrupted sleep due to RLS and periodic limb movement disorder (PLMD). Genes play a role in your risk for these disorders, and there are specific research-based treatments to explore.