Category «Genetics»

Ancestry.com vs 23andMe: Comparing the raw data files

I recently picked up an AncestryDNA kit out of curiosity to find out how well the data matched up to the 23andMe test that I did a few years ago.  Quick answer: It matched up better than I expected. First, a couple of caveats:   I’m not a genealogy expert and was not comparing the …

Review of Genos – Whole Exome Sequencing

UPDATE:  Genos was bought out by another company…  Good reminder to read through privacy policies!  The company that bought them now owns customer’s data but said they would abide by the Genos privacy policy.  I did ask for my data to be deleted and account to be removed out of an abundance of caution. ———— …

How to Download Your 23andMe Data

Someone asked me recently how to download their data from 23andMe.   So, here is a quick tutorial if anyone else is searching for their raw data file on the 23andMe website. Why download your data? It is yours, and it may be something you need in the future.  23andMe could change their policy on …

Checking Your Carrier Status for Genetic Diseases

The term “carrier status” when applied to a genetic disease usually means looking at whether or not you are heterozygous (have one copy) for a mutation that causes a Mendelian genetic disease. Generally, these are the rare diseases that you would need two copies of the variant to have the disease. Take cystic fibrosis as …

Dyslexia – Genetic Connections

Genetics of Dyslexia

While dyslexia is known to run in families, the role of genetics in dyslexia is still being determined.  Here is a quick look at some of the genes thought to be involved in dyslexia, which affects around 10% of the population. Two of the genes (KIAA0319 and DCDC2) identified as probably playing a role in dyslexia …

Creating your own genetics “reports” for free

Reading through some Facebook questions the other day, it hit me that most people are not keeping track of their genetic information for themselves.  There are so many recommendation for ‘reports’ that you can order for $19 or $50 or much more.  A lot of these reports just color your SNPs red or green, which …

Genetics of Grinding Your Teeth

It never fails to amaze me how many of our quirks and traits have a genetic basis.  A study that came out last week caught my eye. Bruxism, teeth grinding, is linked to a genetic variant. The study, Genetic polymorphisms in the serotoninergic system are associated with circadian manifestations of Bruxism, looked into several polymorphisms in …

Mono and genetics

Ever wonder why some people get mono and others don’t?  Almost 95% of adults carry antibodies to the Epstein Barr virus that causes mono, but less than 30% of people are estimated to get mono.  [CDC.gov]   Turns out that there may be a genetic susceptibility to mono as well as environmental factors.  Twin studies, one way …

Ear wax and body odor – it’s genetic

The ABCC11 gene determines both the type of earwax a person has and their armpit odor. A change in a single base in the code for this gene can cause the gene not to function. People with a functioning ABCC11 gene have wet earwax and body odor, while those with the gene variant causing loss of …

PMS, Genetics, and Solutions

PMS, Genetics, Solutions

A LOT of us know the moodiness and inability to think that come with premenstrual syndrome (PMS).  It can range from simply feeling irritable and icky to being something that really interferes with our lives.  Is there something genetic that predisposes some women to PMS?  It has been shown in the past few years that there …