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HIF-1a: Hypoxia, Cancer, and Athletic Superpowers

HIF-1a: Hypoxia, Cancer, and Athletic Superpowers

The hypoxia-inducible factor-1 alpha (HIF1A) gene codes for a transcription factor, that responds to the amount of oxygen available to the cell. This is important in cancer prevention, and several HIF1A genetic variants alter the susceptibility to several types of cancer.

Why Light at Night Increases Cancer Risk

Why Light at Night Increases Cancer Risk

The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)

Checking Your Carrier Status for Rare Genetic Diseases

The term “carrier status” when applied to a genetic disease usually means looking at whether or not you are heterozygous (have one copy) for a mutation that causes a Mendelian genetic disease. While genetic information from 23andMe or a similar DNA test is generally accurate, always re-confirm with a clinical test before making a major health decision. Your results on these variants could be a false positive or a false negative. (Member’s article)

Osteoporosis Genetics and Causes

Osteoporosis: Genetic Susceptibility and Prevention Strategies

Osteoporosis is a degenerative bone disease facing many of us as we age. Genetics plays a big role in susceptibility to osteoporosis. The good news here is that knowing where your genetic susceptibility lies can lead you to targeted, personalized solutions for osteoporosis. (Member’s article)