Your APOE Type and Alzheimer’s Risk: How to Find It, What It Means, and What to Do
Find out your APOE type, understand your Alzheimer’s risk by genotype, sex, and ancestry, and learn about real prevention strategies.
NSAIDs
Mast Cells: MCAS, Genetics, and Solutions
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Fibroids: Genes, Root Causes, and Solutions
Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)
CYP2C8 Pharmacogenetics: Ibuprofen, NSAID Risk, and Arachidonic Acid
CYP2C8 pharmacogenomics: see how variants in this detox gene change the metabolism of ibuprofen and other drugs, influence bleeding risk, and interact with CYP2C9 and supplements.
Alpha-1 Antitrypsin Deficiency: Genetic Raw Data, Carrier Effects, Interactions with TNF
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
CYP2E1: Breaking down alcohol and more
The CYP2E1 enzyme is part of the phase I detoxification system. Discover how variants might affect your alcohol metabolism and more.