Adiponectin levels, food choices, and genetics

Adiponectin, discovered in the 1990s, is a hormone secreted by adipose (fat) tissue. As an anti-inflammatory protein, it protects against the effects of low-grade inflammation associated with obesity.

Although production occurs in adipose tissue, those with more fat tissue usually have lower adiponectin levels. Lower adiponectin levels (and thus high inflammation) have links to chronic issues associated with obesity.[ref]

Additionally, low levels of adiponectin have links to insulin resistance, diabetes, heart disease, and cancer.[ref]

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