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Saturated Fat and Your Genes (ACE gene)

There has been a decades-long debate about which type of fat is best: saturated fat vs polyunsaturated fat.

Those in the paleo and ketogenic world are quick to tout the benefits of saturated fat, while others, such as the American Heart Association, promote polyunsaturated fats[ref]. And most people remain just a bit confused about the arguments on either side…

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Is Saturated Fat Good for You?

It may depend on your genes as to which answer is right for you.

There have been several studies that investigated the effects of a high saturated fat diet on cardiovascular disease – stratified by genetic variants.

Keep in mind that most of these studies are looking at higher saturated fat consumption along with a standard diet (some carbs, some protein, higher fat). The study results may or may not hold true for people on a ketogenic diet.

Let’s take a look at the science so that you can figure out what is right for your genes.


Saturated Fats Genotype Report

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We are all different in our dietary needs. If you have the variants listed above, you may want to decrease the amount of saturated fat in your diet.

Testing specific markers, such as cholesterol levels, could help you determine if decreasing saturated fat is worthwhile for you.

If you carry the ACE deletion/deletion variant:

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About the Author:
Debbie Moon is the founder of Genetic Lifehacks. Fascinated by the connections between genes, diet, and health, her goal is to help you understand how to apply genetics to your diet and lifestyle decisions. Debbie has a BS in engineering from Colorado School of Mines and an MSc in biological sciences from Clemson University. Debbie combines an engineering mindset with a biological systems approach to help you understand how genetic differences impact your optimal health.