Genetic variants can increase pancreatitis risk, along with other factors. Learn the causes of acute and chronic pancreatitis, plus how exocrine pancreatic insufficiency (EPI) drives nutrient deficiencies.
The Nrf2 (Nuclear factor erythroid 2–related factor) signaling pathway regulates the expression of antioxidants and phase II detoxification enzymes. It is a fundamental pathway important in how well your body functions. Your genetic variants in the NFE2L2 gene impact this NRF2 pathway.
CYP17A1 is important in the production of steroid hormones including testosterone and estrogen. SNPs in CYP17A1 impact hormone levels.
The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome. Learn how this opioid antagonist works on the immune system and how your genetics can play a part in its efficacy.
Discover the pros and cons of fluoride for dental health and overall wellness, its sources, toxicity levels, and how genetics influence fluoride sensitivity.
Are you always tired even when you know you slept well? Discover more about the newest research on fatigue and how genetic susceptibility plays a part for some people.
For some people, genetic variants can cause HbA1c levels not to accurately reflect their average blood glucose levels. Find out how your genes impact A1c readings.
Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.
Are you dealing with dry eyes and dry mouth? Sjögren’s syndrome is an autoimmune disorder that affects moisture-producing glands. Discover the underlying causes of Sjögren’s syndrome and the genetic variants that increase susceptibility.
Some people age naturally with beautiful-looking skin. Others slather on creams and odd gunk in a futile battle to chase away wrinkles and age spots. What is the difference? Genetics and environmental factors, of course.
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
Do you have problems with your tennis elbow, rotator cuff, knees, or Achilles tendon? Discover how your genes influence the risk of having tendon problems.
The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.
What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.
Ferritin is the storage protein for iron in the body. Storing too little or too much iron can be an indicator of an underlying problem. Discover the genetic variants that impact ferritin and how to increase ferritin with supplements or foods.
The UGT family of enzymes is responsible for an important part of phase II detoxification. This article explains what the UGT enzymes do in the body, how your genes impact this part of detoxification, and lifestyle factors that can increase or decrease this detox process.
The CYP1A2 gene breaks down caffeine, melatonin, several major prescription drugs, and interacts with smoking. Learn how your genes influence caffeine metabolism and more.
Is it smart to boost your BDNF levels? Discover more by digging into the research studies that show when, how, and why it is important to focus on BDNF.
The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
Rheumatoid arthritis is caused by an immune system attack on the joints, causing thickening and inflammation of the joint capsule. It is caused by a combination of genetic susceptibility and environmental triggers.
Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.
Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.
Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)
One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)