Mercury Detoxification: Genomics and Solutions
What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.
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7 Genetic Variants that Increase your Risk of Blood Clots
Some people are unique in their ability to form clots more easily. This article covers six different genes and the seven genetic variants that increase the risk of blood clots. It is a timely topic because blood clots seem to be a severe complication for people with COVID-19.
Genes that Impact Ferritin Levels
Ferritin is the storage protein for iron in the body. Storing too little or too much iron can be an indicator of an underlying problem. Discover the genetic variants that impact ferritin and how to increase ferritin with supplements or foods.
Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance
The UGT family of enzymes is responsible for an important part of phase II detoxification. This article explains what the UGT enzymes do in the body, how your genes impact this part of detoxification, and lifestyle factors that can increase or decrease this detox process.
Raynaud’s: Causes, Symptoms, and Genetics
Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility.
CYP1A2 Gene: Fast or Slow Caffeine Metabolizer?
The CYP1A2 gene breaks down caffeine, several major prescription drugs, and interacts with smoking. Learn how your genes influence caffeine metabolism and more.
NQO1 Gene: Metabolism of Quinones, Benzene, and More
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article)
Best Supplements to Boost BDNF
Is it smart to boost your BDNF levels? Discover more by digging into the research studies that show when, how, and why it is important to focus on BDNF.
CYP2D6: Medication Interactions, Natural Inhibitors, and Anxiety Traits
The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.
IL-17: Chronic Inflammation & Autoimmune Risk with IL17A, IL17F
The IL17 gene codes for an important part of the immune system. When it is overactive, IL-17 can contribute to the risk of autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease.
Alpha-1 Antitrypsin Deficiency: Genetic Raw Data, Carrier Effects, Interactions with TNF
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
Mushroom Intolerance: Ergothioneine and the OCTN1 Gene
Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.
Rheumatoid Arthritis: Genetics, Root Causes, and Treatment Research
Rheumatoid arthritis is caused by an immune system attack on the joints, causing thickening and inflammation of the joint capsule. It is caused by a combination of genetic susceptibility and environmental triggers.
Nitric Oxide Synthase (NOS3): Heart Health, Blood Pressure, and Healthy Aging
Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.
Lupus: Genetics, Root Causes, and Possible Solutions
Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.
Chronic Sinus Infections: Genetics, Reasons, Solutions
Genetics plays a role in the likelihood of having chronic sinus problems. This article looks at the genetic reasons driving some people to have chronic sinus infections.
Fibroids: Genes, Root Causes, and Solutions
Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)
Advanced Glycation End Products (AGEs): Genetics, lifestyle, and health span
One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)
HIF-1a: Hypoxia, Cancer, and Athletic Superpowers
The hypoxia-inducible factor-1 alpha (HIF1A) gene codes for a transcription factor, that responds to the amount of oxygen available to the cell. This is important in cancer prevention, and several HIF1A genetic variants alter the susceptibility to several types of cancer.
Gingivitis: The Genetic Connection between Gum Disease, Inflammation, and Overall Health
You brush, you floss, and your gums still bleed… perhaps you carry some of the genetic variants associated with gingivitis? Check your genetic data to see. (Member’s article)
Acne: Root Causes & Personal Solutions
Acne is thought to be 80% heritable. Learn how your genetic variants increase your risk of acne and find specific solutions that work for those genetic pathways.
BDNF: Cognition, Stress Resilience, Introversion, and Mood
Low levels of BDNF (Brain-derived neurotrophic factor) are linked to introversion, stress resilience, cognition, and depression levels. Discover ways to increase your BDNF levels and mitigate the problems associated with the BDNF gene variants. (Member’s article)
Why Light at Night Increases Cancer Risk
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
Gulf War Illness: Genetic susceptibility and current research
Many genetic variants have been studied for Gulf War Illness. Take a look into the research behind the illness and discover some possible solutions to help with symptoms.