CYP17A1: Steroid Hormone Production (Testosterone, Estrogen, and DHEA)
CYP17A1 is important in the production of steroid hormones including testosterone and estrogen. SNPs in CYP17A1 impact hormone levels.
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Low-Dose Naltrexone: LDN & Genetics
The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome. Learn how this opioid antagonist works on the immune system and how your genetics can play a part in its efficacy.
Fluoride: Understanding Its Effects on Health
Discover the pros and cons of fluoride for dental health and overall wellness, its sources, toxicity levels, and how genetics influence fluoride sensitivity.
Fatigue: Root Causes, Genetics, Personalized Solutions
Are you always tired even when you know you slept well? Discover more about the newest research on fatigue and how genetic susceptibility plays a part for some people.
HbA1c: Heritability of A1C Testing
For some people, genetic variants can cause HbA1c levels not to accurately reflect their average blood glucose levels. Find out how your genes impact A1c readings.
Genetics and Intelligence: IQ-Influencing Genes and Paths to Optimization
Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.
Sjogren’s: Causes, Genes, Solutions
Are you dealing with dry eyes and dry mouth? Sjögren’s syndrome is an autoimmune disorder that affects moisture-producing glands. Discover the underlying causes of Sjögren’s syndrome and the genetic variants that increase susceptibility.
Skin Aging: Using Genomics to Solve Wrinkles and Age Spots
Some people age naturally with beautiful-looking skin. Others slather on creams and odd gunk in a futile battle to chase away wrinkles and age spots. What is the difference? Genetics and environmental factors, of course.
Why Light at Night Increases Cancer Risk
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
Tendinitis (Tendonitis): Genes, Inflammation, and Targeted Solutions
Do you have problems with your tennis elbow, rotator cuff, knees, or Achilles tendon? Discover how your genes influence the risk of having tendon problems.
CYP2B6: Genetic Variants That Interact with Medications
The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.
Mercury Detoxification: Genomics and Solutions
What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.
Genes that Impact Ferritin Levels
Ferritin is the storage protein for iron in the body. Storing too little or too much iron can be an indicator of an underlying problem. Discover the genetic variants that impact ferritin and how to increase ferritin with supplements or foods.
Glucuronidation: UGT Genetic Variants, Detoxification, and Hormone Balance
The UGT family of enzymes is responsible for an important part of phase II detoxification. This article explains what the UGT enzymes do in the body, how your genes impact this part of detoxification, and lifestyle factors that can increase or decrease this detox process.
CYP1A2 Gene: Fast or Slow Caffeine Metabolizer and More
The CYP1A2 gene breaks down caffeine, melatonin, several major prescription drugs, and interacts with smoking. Learn how your genes influence caffeine metabolism and more.
Best Supplements to Boost BDNF
Is it smart to boost your BDNF levels? Discover more by digging into the research studies that show when, how, and why it is important to focus on BDNF.
CYP2D6: Medication Interactions, Natural Inhibitors, and Anxiety Traits
The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.
IL-17: Chronic Inflammation & Autoimmune Risk with IL17A, IL17F
The IL17 gene codes for an important part of the immune system. When it is overactive, IL-17 can contribute to the risk of autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease.
Alpha-1 Antitrypsin Deficiency: Genetic Raw Data, Carrier Effects, Interactions with TNF
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
Rheumatoid Arthritis: Genetics, Root Causes, and Treatment Research
Rheumatoid arthritis is caused by an immune system attack on the joints, causing thickening and inflammation of the joint capsule. It is caused by a combination of genetic susceptibility and environmental triggers.
Nitric Oxide Synthase (NOS3): Heart Health, Blood Pressure, and Healthy Aging
Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.
Lupus: Genetics, Root Causes, and Possible Solutions
Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.
Chronic Sinus Infections: Genetics, Reasons, Solutions
Genetics plays a role in the likelihood of having chronic sinus problems. This article looks at the genetic reasons driving some people to have chronic sinus infections.
Fibroids: Genes, Root Causes, and Solutions
Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)
Advanced Glycation End Products (AGEs): Genetics, Lifestyle, and Health Span
One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)