TNF-alpha is a key inflammatory cytokine linked to autoimmune, cardiovascular, mood, and neurodegenerative diseases. Learn how TNF gene variants affect your risk and potential natural TNF inhibitors.
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article)
IL-2 dysregulation affects long COVID, autoimmune diseases, and cancer therapy response. Learn about your IL-2 genetic variants and natural ways to support IL-2.
Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility.
ABCB1 encodes P-glycoprotein, a transporter that removes toxins – and medications – from the body. Genetic variants in the ABCB1 gene can affect how well a medication works for you.
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Mycotoxins from food and water-damaged buildings are cleared via CYP450, GST, and UGT pathways. Variants in these detox genes explain why mold and mycotoxin sensitivity varies.
Epstein-Barr virus (EBV) impacts lifelong health, links to autoimmune diseases, genetic risk factors, and practical steps to reduce reactivation.
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Discover the impact of the BPIFB4 gene on longevity and immunity, and find out if you have the longevity variant in your genotype report.
Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.
Learn how common genetic variants in F2, F5 (Factor V Leiden), ITGB3, VWF, GP6, and F11 can increase your risk of blood clots, DVT, heart attack, and stroke
Genetics plays a role in the likelihood of having chronic sinus problems. This article looks at the genetic reasons driving some people to have chronic sinus infections.
High blood lead levels are influenced by exposure and by genetic variants. Learn how your genes impact lead levels, and what to do about it.
For some people, back pain is a daily occurrence that drastically affects their quality of life. For others, it may be an intermittent nagging problem, often without rhyme or reason. Your genes play a role in whether disc degeneration gives you back pain.
The IL17 gene codes for an important part of the immune system. When it is overactive, IL-17 can contribute to the risk of autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease.
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Psoriasis is an autoimmune condition that causes dry, sometimes itchy patches of skin. It is caused by the immune system attacking your skin cells, speeding up the turnover of the cells. Genetics plays a role in your susceptibility.
MRGPRX2 is a recently discovered mast cell receptor. It is linked to drug hypersensitivity reactions as well as asthma, rosacea, and IBD.
You brush, you floss, and your gums still bleed… perhaps you carry some of the genetic variants associated with gingivitis? Check your genetic data to see. (Member’s article)
Inflammation and breakdown of cartilage are at the root of osteoarthritis. Learn how your genes impact the pathways involved in arthritis.
Not all type 2 diabetes risk is from what you eat… Genetics plays a big role in diabetes. Learn more about your genetic susceptibility.
Acne is up to 80% genetic. Learn how your genes, hormones, diet, and inflammation drive breakouts—and get personalized, research-backed solutions using your 23andMe or AncestryDNA data.