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COMT: How to Optimize Your Supplements for Your COMT Genotype

Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.

Anxiety: Genetics, heredity, and personalized solutions

When it comes to anxiety, genetic variants combine with environmental factors (nutrition, sleep, relationships, etc) when it comes to anxiety. Understanding your anxiety genes can help you figure out which pathways to target.

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

GABA: Genetics, Anxiety, and Immune Response

GABA (gamma-Aminobuyteric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions, including anxiety and PTSD.

MTHFR, depression, anxiety, symptoms and treatment

We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.

CYP2D6 gene and medication reactions

The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.

CBD Oil: Will it work for you?

Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.

COMT Gene: Neurotransmitter levels and estrogen metabolism.

Wondering why your neurotransmitters are out of balance? It could be due to your COMT genetic variants. The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine, and norepinephrine.