Very Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
VLCAD deficiency causes the mitochondria to be unable to use long-chain fatty acids for energy production. This can result in hypoglycemia or mitochondrial dysfunction.
Mitochondria
Mitochondrial energy is at the heart of cellular health, impacting longevity, chronic disease, fatigue, and more.
Where to start?
- Check out NAD+: Nicotinamide Riboside or NMN for mitochondrial energy
- View your SIRT3 gene SNPs
- Find out how CoQ10 impacts mitochondrial energy production
Members: Be sure to check out the Mitochondria Topic Summary for a quick overview of all your genetic variants related to your athletics and exercise.
Latest articles on Mitochondria Genes:
Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health
Learn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs.
Thiamine: Genomics, Cellular Energy, and Cognitive Function
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.
Medium Chain Acyl-CoA Dehydrogenase Deficiency: Check your genetic data
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is an “inborn error of metabolism” which impairs the body’s ability to break down medium-chain fatty acids for fuel. Learn more about this metabolic disorder.
Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification
Glutathione is an antioxidant produced in all cells to balance out ROS. Genetic variants can impact your glutathione levels, which can alter your ability to detoxify certain substances or withstand stressors in the body.
Pyruvate Dehydrogenase Deficiency – Mitochondrial Dysfunction and Lactate Production
Pyruvate Dehydrogenase is central to cellular energy production. Learn about its role in energy production, genetic mutations, association with ME/CFS and Long Covid, and strategies to manage its deficiencies.
Mold Genes: How mold and mycotoxins interact with genetics
Exposure to certain kinds of mold can cause chronic, negative health effects. Discover how genetic variants impact the ability to handle mycotoxins.
Red Light and Photobiomodulation: ATP from Photons
Red and near-infrared wavelengths of light interact with mitochondria to produce ATP. Learn why – and discover how mitochondrial genes may play a role.
Creatine: Boosting Muscles and Increasing Brain Power
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Biotin Deficiency: Genetic Reasons for Increasing Biotin
Biotin, also known as vitamin B7 or vitamin H, is a cofactor that aids in the metabolism of fats, carbohydrates, and proteins. Biotin deficiency due to diet is pretty rare, but there are genetic variants that can increase your risk for biotin deficiency or insufficiency.
Statins and Brain Fog: Exploring how statins impact memory and cognitive function
Understand the connection between statin use and brain fog. Dive into the research on how cholesterol-lowering drugs impact cognitive health and memory.
CoQ10: Genes, Benefits, and Mitochondrial Energy
CoQ10, or ubiquinone, is an integral part of mitochondrial energy production. It is also used as a lipid-soluble antioxidant. Learn how age and genes affect it.
Alpha-Ketoglutarate: A Key to Healthspan and Fighting Age-Related Diseases
Supplementing with Alpha-ketoglutarate (αKG) might be beneficial for longevity since it plays a role in energy production and inflammation reduction.
SIRT3, Aging, and Mitochondrial Function
How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.
Trying to get pregnant? Targeted Approaches to Improving Egg Quality
Trying to get pregnant? Healthy eggs are vital for a successful pregnancy. Discover four key ways to improve your egg quality, according to research studies.
Multiple Sclerosis: Genetic Factors and Susceptibility to MS
MS susceptibility is linked to both genetic causes and environmental factors. Learn how those two combine – and possible solutions.
Arsenic Detoxification and Your Genes
Arsenic exposure occurs via well water, in certain foods, and through breathing. This article covers the pathways the body uses to get rid of arsenic, and it includes information on genetic variants that may impair the detoxification of arsenic.
Depression, Genetics, and Mitochondrial Function
How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
Inclusion Body Myositis: Genomics and Solutions
Inclusion body myositis is a progressive, chronic condition that causes muscle weakness. It may be an interplay between inflammation, the dysregulation of proteins, mitochondrial dysfunction, and changes to autophagy. Somewhere in the mix, autoimmunity may be triggering it.
Short-chain Acyl-CoA Dehydrogenase Deficiency
If you have tried fasting or perhaps a ketogenic diet and felt horrible, there could be a genetic reason. You might carry a genetic mutation that causes SCADD (short-chain acyl-CoA dehydrogenase deficiency).