Reelin – Long Covid, Depression, and Alzheimer’s
Reelin is a key glycoprotein involved in brain development, cognition, and neurodegenerative diseases like Alzheimer’s, schizophrenia, autism, and cardiovascular health.
Mood & Mental Health
OCD: Obsessive-Compulsive Disorder Genes
Genetic variants play a role in susceptibility to obsessive-compulsive disorder. Understanding your genes may help you understand OCD better and help you to target the right treatment.
HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
Schizophrenia: Genetic and Environmental Factors
Schizophrenia is a complex disease caused by a combination of genetic susceptibility along with environmental factors. Research points to multiple pathways involved in schizophrenia and schizoaffective disorder.
Is Inflammation Causing Your Depression and Anxiety? The Science Behind the Link
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Anxiety: Genetics, heredity, and personalized solutions
When it comes to anxiety, genetic variants combine with environmental factors (nutrition, sleep, relationships, etc) when it comes to anxiety. Understanding your anxiety genes can help you figure out which pathways to target.
Underlying Cause(s) of Depression: Leveraging Your Genetic Data
Depression can have multiple physiological causes. This article ties together 9 separate articles on depression to simply your genetic search.
Psychopaths: Born not made?
Can you be born a psychopath? Are there genes linked to psychopathy? Discover how your genes don’t predestine you to become a psychopath.
Depression, Genetics, and Mitochondrial Function
How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
MTHFR, Depression, Anxiety, Symptoms and Treatment
We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.
ANK3: Bipolar Disorder and Brain Development
The genetic variants in the ANK3 gene impact the risk of psychiatric disorders that include bipolar disorder and autism spectrum disorders, and heart arrhythmia. Discover how ANK3 impacts neuronal formation and transmission and how this ties into an increased risk of psychiatric disorders.
Circadian rhythm disruption as a root cause of depression
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
Genetics and Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
Bipolar Disorder, Depression, and Circadian Clock Genes
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.
The Interaction Between BDNF and Serotonin
Genetic variants in the BDNF and serotonin receptor genes combine to increase the risk of depression and anxiety. Learn more about BDNF and how these variants interact — and check your genetic data to see how this applies to you.
Resilience: Genetic Variants Involved in Surviving Childhood Trauma
Exposure to childhood trauma, such as exposure to abuse, violence, or repeated stress, can have a long-lasting effect. Genetic differences in the CRHR1 gene are linked to elevated cortisol levels in adults who were exposed to trauma in childhood.
Circadian Rhythm Genes: Mood Disorders
Circadian rhythm disruption can drive mood disorders. Learn more about the genes involved and the ways to normalize your circadian rhythm.