Circadian clock gene variants in CLOCK, BMAL1, PER, CRY, NPAS2, and OPN4 interact with light exposure to disrupt hormones, sleep, and mood, increasing risk for depression, anxiety, and seasonal affective disorder.
Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Melanopsin is the receptor for blue light. It is found in the retina, skin, adipose tissue, and blood vessels. Genetic variants can impact reaction to blue light.
Some people age naturally with beautiful-looking skin. Others slather on creams and odd gunk in a futile battle to chase away wrinkles and age spots. What is the difference? Genetics and environmental factors, of course.
Sleep quality is essential for good health and our genetics play a role in how much slow wave sleep we naturally get.
Is it smart to boost your BDNF levels? Discover more by digging into the research studies that show when, how, and why it is important to focus on BDNF.
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
Lynch Syndrome increases the risk of certain cancers. The cause relates to inherited mutations in the genes responsible for stopping the replication of cancerous cells. Learn how cancer occurs, risks involved with this particular syndrome, and prevention strategies to implement for risk reduction
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
Lupus is a complex autoimmune disease that can impact several different systems in your body. Learn more about how your genetic variants impact the “why” for this autoimmune disease.
Your circadian rhythm influences your immune response. Learn how this rhythm controls white blood cell production and why melatonin protects against viral and bacterial infections.
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.
A core circadian rhythm gene, BMAL1, influences heart disease risk, diabetes, and cancer. Check your genes and learn how to mitigate the risk.
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
The body’s circadian clock regulates many different functions over the course of a 24-hour day. The genes that code for different parts of the circadian clock have a wide-ranging effect on sleep, mood, and overall health.