Alzheimer’s Disease

Alzheimer’s disease risk is partly influenced by genetic variants in the APOE gene.

If you want to know whether you are at a higher risk for Alzheimer’s disease, this article will walk you through how to check your 23 and Me or other genetic data for the APOE E4 variant.

Click here to check your genetic data for Alzheimer’s and APOE genotype

Recent articles on Alzheimer’s Disease:

Serotonin 2A receptor variants: psychedelics, brain aging, and Alzheimer’s disease - Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging and Alzheimer's.
TREM2 and Alzheimer’s Disease Risk - The TREM2 gene is important in how the brain's immune system functions. Learn how variants in this gene impact the risk for Alzheimer's disease.
SOD1: Genetic Variants in Our Antioxidant Defense System - Our body has built-in antioxidants that fight against cellular stress. The superoxide dismutase enzyme fights against oxidative stress in your cells. 
research on lithium orotate, Alzheimer's, mood Lithium Orotate: Mood, Alzheimer’s, and Aging - Researchers found that Texas counties with higher levels of lithium in their groundwater had less of an increase in Alzheimer's rates compared with counties that had lower levels of lithium. This isn't a total surprise since previous studies had linked lithium to a decreased risk of dementia, but it is a great confirmation at a large scale population level. 
A Klotho Gene Variant Reduces Alzheimer’s Risk for APOE E4 Carriers - The Klotho protein is involved in many of the diseases of aging. Learn more about this gene and find out how your Klotho variants may impact healthy aging.
alzheimer's Alzheimer’s and APOE genotype - The APOE gene variants are tightly linked with the risk of Alzheimer's disease. Find out whether you carry the APOE risk type for Alzheimer's - and learn what all of us can do via diet and lifestyle to prevent this disease.
Prions: When proteins go awry - Prions are able to infect, causing the normal protein around them to also misfold. These misfolded proteins aggregate to cause neurogenerative disease. Susceptibility to prion diseases depends in part on your genes.
alzheimer's Genetic Mutations that Protect Against Alzheimer’s Disease - Just like there are genetic variants that increase the risk of Alzheimer's, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member's article)
Melatonin receptor gene: Alzheimer’s risk and night shift work - Shift work and ‘social jet lag’ are linked to an increased risk for several chronic diseases. A genetic variant in the MTNR1A gene impacts melatonin receptors in the brain. (Member's article)
preventing alzheimer's Alzheimer’s and Light at Night: Taking action to prevent this disease - Too much blue light at night is standing out as a player in circadian rhythm dysfunction and can increase your risk of Alzheimer's disease. Discover ways to improve your sleep quality and environment to help lower your modifiable risk.