Advanced Glycation End Products
Recent research shows that advanced glycation end products (AGEs) are a causative factor in many degenerative diseases – including almost all of the diseases associated with aging. AGEs have been linked to Alzheimer’s, heart disease, diabetes, chronic kidney disease, wrinkles and loss of skin…
NAD+ Reversing Aging? Overview of NR and NMN
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are two supplements that have taken the longevity and anti-aging world by storm. With animal studies showing exciting results including reversal of age-related diseases, these supplements are an exciting glimpse into the future of reversing aging. Just…
Prions: When proteins go awry
What is non-living, doesn’t have DNA but yet can infect, replicate, and eventually cause death? Sounds like either a really bad riddle or an episode of the Walking Dead… The answer is a type of protein called a prion. Prions are a bit hard…
BChE – Pesticides, Parkinson’s, and Potatoes
The BCHE gene codes for the butyrylcholinesterase enzyme. The BChE enzyme is found in the plasma of the blood. It is a cholinesterase which breaks apart choline esters, such as acetylcholine. Acetylcholinesterase is a similar enzyme that is responsible for breaking down the neurotransmitter,…
Melatonin: Key to Health and Longevity
It seems like everything that I’ve written about lately has a common thread: melatonin. When I started weaving together all those melatonin threads, a big picture was revealed. You could say it is a… tapestry of health. Melatonin may actually be the key to…
Are you exhausted by shift work? It could be genetic.
Genetics plays a role in how much shift work impacts you. While some people may get along well with shift work, others may experience more difficulties with it. A new study found one genetic variant that may shed some light on the topic (pun intended :-).
Lithium: A mineral that affects mood, Alzheimer’s disease, obesity, and telomeres
Researchers found that Texas counties with higher levels of lithium in their groundwater had less of an increase in Alzheimer’s rates compared with counties that had lower levels of lithium. This isn’t a total surprise since previous studies had linked lithium to a decreased risk of dementia, but it is a great confirmation at a large scale population level.
Alzheimer’s and Light at Night: Taking action to prevent this disease
Light at night and the link to Alzheimer’s disease. Animal studies show that disrupting circadian rhythm with light at night causes an increase in amyloid plaque accumulation.
Building Up Iron: Check your genes to see how iron affects your health
Hemochromatosis is a fairly common genetic disease that causes iron to build up in the body. Knowledge is power here. Knowing that you carry the genetic variants for hemochromatosis can literally add years to your life since you can prevent the buildup of iron…
SOD1: Genetic Variants in Our Antioxidant Defense System
Superoxide dismutase 1 (SOD1) is the gene that codes for the copper-zinc superoxide dismutase enzymes which help protect against oxidative stress and detoxify reactive oxygen species. Three types of superoxide dismutases are part of our built-in antioxidant system: SOD1, found in the cytosol or…