Explore the genetic basis of POTS, from HLA and norepinephrine transporter variants to EDS, MCAS, and long Covid connections, plus strategies to better manage symptoms.
The research on melatonin shows that it plays an important role in our body’s inflammatory response to pathogens. Learn more about the current research on melatonin for COVID-19 and the science behind how it impacts immune response.
Is it smart to boost your BDNF levels? Discover more by digging into the research studies that show when, how, and why it is important to focus on BDNF.
Serotonin is a neurotransmitter that is important in depression, sleep, and many other aspects of health. Learn how your genetic variants in the serotonin receptor genes impact their function.
An examination of the current research for the ‘God gene’, explaining what it does and its importance in Parkinson’s disease.
The FTO gene is nick-named the ‘fatso gene’ because of its association with obesity. This article digs into the current research on the FTO gene and then will give you some science-based options for controlling your weight if you carry the FTO genetic variant.
Learn about how genetic variants in certain inflammatory cytokines can increase or decrease the risk of recurrent miscarriage.
Rapamycin is an antibiotic used as an immunosuppressant, an anti-cancer agent, and to prevent blocked arteries. Rapamycin is now the focus of longevity and healthspan-extending research by inhibiting mTOR.
This article covers what the research shows about folate metabolism, MTHFR, and immune response. See what the research says.
We all vary in how well we convert the plant-based omega-3 oils into the DHA and EPA that our body needs. Some people are really poor at this conversion and thus should either eat more fish or consider taking a DHA / EPA supplement. Learn more about how your variants might affect your health.
Wondering what MTHFR is all about? Learn what the research says about it and how to check your own raw data file.
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging, and Alzheimer’s.
Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.
This is a quick (Member’s Only) overview of how your genetic variants impact various aspects of sleep including insomnia, circadian rhythm, and sleep quality.
This article digs into how the genetic variants you inherited from mom and dad influence the bacteria that can reside within you and how dietary changes can make a difference.
Grinding your teeth at night can be due, in part, to genetic variants in the serotonin genes.
The MTHFR C677T variant increases the risk of migraines. Learn how to check your genetic data and how to mitigate the risk.
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
Key takeaways: The MTHFR enzyme converts folate (vitamin B9) to its active form, 5-MTHF. Folate is used to create methyl groups, which cells use to synthesize neurotransmitters, detoxify toxicants, methylate DNA, and maintain a healthy heart. The common MTHFR C677T and A1298C variants lower enzyme function (up to ~70–80% for … Read more
The genetic variants in the ANK3 gene impact the risk of psychiatric disorders that include bipolar disorder and autism spectrum disorders, and heart arrhythmia. Discover how ANK3 impacts neuronal formation and transmission and how this ties into an increased risk of psychiatric disorders.
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
BookmarkStudy title: Evening home lighting adversely impacts the circadian system and sleep Nature, Nov 2020 Overview of the study: Quick background: Melatonin is a hormone that the body produces at night, and it is an integral part of our circadian rhythm. Levels rise at night when it is dark, and … Read more
Studies show that lithium in ground water is linked to lower levels of Alzheimers, depression, and aggression. Find out how lithium may be important in Alzheimer’s prevention.
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
PPARδ is a key player in how and when your muscles burn fat for fuel. Genetic variants in the PPARD gene impact how well your muscles utilize fatty acids. These variants also impact how much of a fat-burning benefit you get from exercise.