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Folate Optimization: MTHFR and Fertility

MTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.

Melatonin: Key to Health and Longevity

More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.

Ghrelin: The hunger hormone

The hunger hormone, ghrelin, is important in appetite regulation and satiety. Learn how your genes interact with your diet when it comes to ghrelin levels. (Member’s article)

Research studies on melatonin and SARS-CoV-2

The research on melatonin shows that it plays an important role in our body’s inflammatory response to pathogens. Learn more about the current research on melatonin for COVID-19 and the science behind how it impacts immune response.

Diabetes: Genetic Risk Factors

A printable guide for the genetic risk factors of diabetes. It includes specific genotypes that influence the risk of diabetes, along with possible lifestyle changes that can be implemented for better outcomes.

MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

Sleep Report: Genetic Causes of Sleep Problems

This is a quick (Member’s Only) overview of how your genetic variants impact various aspects of sleep including insomnia, circadian rhythm, and sleep quality.

FADS1 and FADS2: Omega-3 and Omega-6 Fatty Acids

We all vary in how well we convert the plant-based omega-3 oils into the DHA and EPA that our body needs. Some people are really poor at this conversion and thus should either eat more fish or consider taking a DHA / EPA supplement. Learn more about how your variants might affect your health.

how to check your 23andMe data for MTHFR mutation

MTHFR: How to check your data for C677T and A1298C

Key takeaways: ~ The MTHFR gene impacts how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. ~ Genetic variants can impact how well this gene works. ~ Optimizing diet and supplements related to methylation may impact several aspects of wellness. Check your raw data for C677T, A1298C, and more This article shows you what to check in your raw data, then explains the scientific research on the MTHFR variants. At the end of the article, you will find solid, evidence-based lifestyle solutions for optimizing the MTHFR variants. Frankly, there is a lot of misinformation on the internet about the MTHFR gene mutations, so I will explain the peer-reviewed research studies here. I’ll clearly explain how to optimize your diet (or add in supplements) if you carry MTHFR genetic variants. MTHFR Gene Mutations Genotype Report: Let’s put the rest of this article into context by checking your two more common MTHFR variants first. (I’ll include other MTHFR variants later in the article). You don’t need to do specific genetic testing or buy health … Read more

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PRO Members: Learning Resources

As a busy professional, your time is precious. These learning resources are designed to give you the essentials in a fast, visual format.

Genetics of Mannose-Binding Lectin Deficiency

Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infections. Find out how genetic variants in this system increase your susceptibility to specific pathogens.

FTO is more than just an obesity gene

FTO and m6A methylation: From COVID to Cancer to Obesity

The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.

The LDLRAP1 Gene: What does it do?

This article offers a quick description of the LDLRAP1 gene with Genetic Lifehacks articles that include LDLRAP1 variants (SNPs).

Maca Root: Research-backed Benefits and How It Works

Explore the benefits of Maca root, a cruciferous vegetable with adaptogenic properties, known for balancing hormone levels and aiding menopausal symptoms. Learn about its potential side effects, gene interactions, and the science behind its unique bioactive compounds.

Blood clots, platelets, and adenoviruses

Take a look into the role of platelets, their connection to blood clots, and a discussion of the research on adenovirus-vector therapy, thrombocytopenia, and platelet reactions.