There are multiple causes of irritable bowel syndrome (IBS), and genetics can definitely play a role in IBS symptoms. Pinpointing your genetic cause may help you to figure out the right solution for you. (Member’s article)
Genetic variants in DAO and HNMT genes affect histamine breakdown. Check your AOC1, HNMT, and HDC genotype. Low-histamine diet, DAO supplements, and more.
Thiamine (vitamin B1) is essential for energy production and brain function. Learn how SLC19A2, SLC19A3, and other genes affect your need for thiamine.
Multiple Chemical Sensitivity involves systemic reactions to low-level chemical exposures. Genetic research points to detox enzyme variants and olfactory gene interactions.
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Alpha-gal syndrome causes allergic reactions to meat (beef, pork, lamb) after being bitten by a tick. Find out why and which genetic pathways are involved.
A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This can alter the gut microbiome – but protect against Norovirus infections.
Non-alcoholic fatty liver disease (NAFLD) can be caused by genetic susceptibility, diet, and lifestyle factors. The good news is that fatty liver disease is reversible.
Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Fructose intolerance can be due to a rare mutation in the ALDOB gene or it can be due to reduced intestinal absorption.
Nickel allergy: Explore how genes, everyday exposures, and diet contribute to nickel sensitivity, including rashes, GI symptoms, and brain fog.
Berberine, a natural compound, is found in plants such as Oregon grape, barberry, and goldenseal. It has been a staple of Traditional Chinese Medicine for thousands of years. Take a look into the research and health benefits of this age-old compound.
Pernicious anemia is a B-12 deficiency anemia caused by an autoimmune attack on the cells that produce intrinsic factor. Learn how genes impact susceptibility to pernicious anemia.
Your genes control whether you are likely to produce lactase as an adult. Check your 23andMe or other genetic data to see if you are likely to enjoy a big glass of milk.
Some clinicians recommend a low sulfur diet for people with CBS mutations. Find out what the research shows – and why that recommendation is not backed up. (Member’s article)
The low-FODMAPs diet is often recommended as a starting point for anyone with IBS symptoms but genetics can limit its effectiveness.
Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.
All of the general advice, fix your gut, eat more fiber, eat fermented foods, avoid sugar, grains, dairy, etc., may work for some but not for everyone. Take a good look at some of the genes that affect our microbiome.