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Nicotinamide Riboside and NMN: Boosting NAD+ in Aging

Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.

Will you go bald? Genetics and hair loss

What causes male pattern baldness? A combination of genetics, nutrition, and environmental toxins come together to form the risk factors for baldness. But genetics really seems to rule the roost here.

SIRT3, Aging, and Mitochondrial Function

How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.

Tryptophan Pathways: Kynurenine, Serotonin, and Melatonin

Tryptophan is an amino acid that the body uses to make serotonin and melatonin. Genetic variants can impact the amount of tryptophan that is used for serotonin. This can influence mood, sleep, neurotransmitters, and immune response.

Depression genes

Depression, genetics, and mitochondrial function

How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.

woman with pregnancy test in hand

Genetic links to infertility for women

Your genes may be playing a role in your infertility — and knowing which genetic variants you carry may help you figure out solutions to try.

Inclusion Body Myositis: Genomics and Solutions

Inclusion body myositis is a progressive, chronic condition that causes muscle weakness. It may be an interplay between inflammation, the dysregulation of proteins, mitochondrial dysfunction, and changes to autophagy. Somewhere in the mix, autoimmunity may be triggering it.

Age-Related Macular Degeneration Genes

Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly. You will find supplements specifically promoted for preventing AMD. This article explains age-related macular degeneration, delves into the genetic risks, and then explains which supplements are likely to be protective and which may do more harm than good.

Advanced Glycation End Products (AGEs): Genetics, lifestyle, and health span

One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)

HIF-1a: Hypoxia, Cancer, and Athletic Superpowers

The hypoxia-inducible factor-1 alpha (HIF1A) gene codes for a transcription factor, that responds to the amount of oxygen available to the cell. This is important in cancer prevention, and several HIF1A genetic variants alter the susceptibility to several types of cancer.