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COMT supplement interactions, slow COMT, fast COMT, SNP

COMT: How to Optimize Your Supplements for Your COMT Genotype

Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.

COMT Graphical Abstract, Slow COMT effects, Slow COMT

COMT Gene: Neurotransmitter Levels, Estrogen Metabolism, and SNPs

Wondering why your neurotransmitters are out of balance? It could be due to your COMT genetic variants. The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine, and norepinephrine.

COMT and Chronic Pain, Fibromyalgia, chronic back pain, natural supplements to avoid for slow COMT

COMT in Pain Disorders

Genetic polymorphisms in COMT affect how we feel certain types of pain. These variants are linked to increased susceptibility to chronic pain disorders.

Anxiety Genes, ANDORA2A, BDNF, Lion's mane for anxiety

Anxiety: Genetics, heredity, and personalized solutions

When it comes to anxiety, genetic variants combine with environmental factors (nutrition, sleep, relationships, etc) when it comes to anxiety. Understanding your anxiety genes can help you figure out which pathways to target.

MTHFR mutations explained, frequency of C677T SNP, A1298C SNP, Supplement Interaction, MTHFR variant risks

MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

Dopamine Fasting: Addicted to the internet?

Genetics plays a role in susceptibility to addictive behavior, including internet and smartphone addiction. This article examines the latest fad of dopamine fasting along with genetic variants tied to internet use problems, smartphone usage disorder, and gaming disorders.

Estrogen metabolism, estrogen metabolites that increase cancer risk, estrogen genetic variants, steps to keep estrogen in balance

Estrogen: How It Is Made and How We Get Rid of It

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.

Pernicious Anemia: Genomics and B12 Deficiency

Pernicious Anemia: Genomics and B12 Deficiency

Pernicious anemia is a B-12 deficiency anemia caused by an autoimmune attack on the cells that produce intrinsic factor. Learn how genes impact susceptibility to pernicious anemia.

Are you genetically less likely to get the flu?

Have you ever wondered why some people never seem to get the flu when it is going around? Simply put, some people are just more susceptible to getting the flu than others. Learn more and see if you are more or less susceptible to the flu.

Age-Related Macular Degeneration Genes

Age-Related Macular Degeneration Genes

Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly. You will find supplements specifically promoted for preventing AMD. This article explains age-related macular degeneration, delves into the genetic risks, and then explains which supplements are likely to be protective and which may do more harm than good.

Luteolin: Anti-inflammatory Neuroprotective, Antihistamine, food high in luteolin, genetic

Luteolin: Antihistamine, Memory, and Brain Fog

New research suggests the benefits of luteolin (a flavonoid found in fruits, vegetables, and herbs) may include anti-inflammatory and neuroprotective properties.

MTHFR variants and depression and anxiety

MTHFR, Depression, Anxiety, Symptoms and Treatment

We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.

Supplements with genetic connections

Supplements with Genetic Connections

Linking supplements and genetic SNPs so that you can more easily find out what may work for you – and what to be cautious about.

Vitamin E, Genetics, and Inflammation

Vitamin E, Genetics, and Inflammation

Vitamin E, an antioxidant, is often promoted to prevent cardiovascular disease and LDL cholesterol oxidation. New research shows a genetic component to whether a person benefits from supplementation. Find out more by checking your genetic data.

Asprin, Heart Disease Prevention, and Genetics

Asprin, Heart Disease Prevention, and Genetics

While large population studies show the benefits of aspirin, research shows that these heart-health benefits are dependent on your genes. Find out more and check your genetic raw data.

PRO: Supplement Research Connections

Pro Member resource guide to help navigate popular supplements concerning genetic variants and health topics. You will find links to all corresponding articles to help you narrow down areas of interest.

MTR and MTRR genetic variants, Vitamin b12 genetic variants, choosing the right form of B12 for your genetic variants

MTR & MTRR, Vitamin B12, and Methylation

There are several genes that can influence your absorption, transport, and need for vitamin B12. Some people need higher amounts of B12, and some people thrive on different forms of B12. Take a look at your genetic data to see if you should up your intake of B12.