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COMT in Pain Disorders

Genetic polymorphisms in COMT affect how we feel certain types of pain. These variants are linked to increased susceptibility to chronic pain disorders.

COMT: How to Optimize Your Supplements for Your COMT Genotype

Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.

COMT Gene: Neurotransmitter levels and estrogen metabolism.

Wondering why your neurotransmitters are out of balance? It could be due to your COMT genetic variants. The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine, and norepinephrine.

Rosacea, genetics, and solutions

Rosacea is a chronic inflammatory skin condition that is driven by upregulated inflammation. Learn how your genes interact with environmental factors to cause rosacea.

Estrogen: How it is made and how we get rid of it

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.

Familial Mediterranean Fever: Mimics fibromyalgia, arthritis, inflammation

Familial Mediterranean fever (FMF) is a genetic condition of inflammatory episodes that cause painful joints, pain in the abdomen, or pain in the chest. It is most often accompanied by a fever. FMF is often misdiagnosed as various pain-related conditions such as fibromyalgia, myofascial pain syndrome, or gouty arthritis.

featured image representing a scale with subtle adenovirus es on it.

Adenoviruses: Causing Weight Gain and Obesity

There have been several interesting studies linking obesity to a viral infection, specifically an adenovirus. Learn more about this virus and its association with obesity.

Nicotinamide Riboside and NMN: Boosting NAD+ in Aging

Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.

Supplements with Genetic Connections

Linking supplements and genetic SNPs so that you can more easily find out what may work for you – and what to be cautious about.

Homocysteine: Genetics and Solutions

High homocysteine levels are strongly linked to an increased relative risk of cardiovascular diseases. Find out how your genes impact homocysteine levels.

Chronic Lyme: Genetic Susceptibility

The interesting thing about Lyme disease is that the genetic variants you carry impact both how the disease affects you and how well antibiotics work for you. Learn whether your genetic variants are linked to post-treatment Lyme disease symptoms such as joint pain. (Member’s article)

Naltrexone: LDN & Genetics

The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome. Learn how this opioid antagonist works on the immune system and how your genetics can play a part in its efficacy.