BMAL1: Core circadian gene with links to heart disease, cancer, and diabetes
A core circadian rhythm gene, BMAL1, influences heart disease risk, diabetes, and cancer. Check your genes and learn how to mitigate the risk.
Heart Health
Heart disease is the number one cause of death, making heart health a priority for everyone!
Heart disease, though, is a catch-all term that applies to many different conditions. These articles will show you where your genetic susceptibility lies – and what to do about it.
Member’s: Check out the Heart Health Topic Summary Report for a quick overview of all your genetic variants related to heart health.
High blood pressure due to AGTR1 gene variants
There are several causes of high blood pressure. Genetic variants in the AGTR1 gene are strongly linked with blood pressure and there are specific lifestyle changes that should work to change your blood pressure if you carry the variants.
Will statins give you muscle pain?
Statins are one of the most prescribed medications in the world. One side effect of statins is myopathy, or muscle pain and weakness. Your genetic variants are significant in whether you are likely to have side effects from statins.
ITGB3: the PIA1/A2 variant and clotting
The PIA2 variant of the ITGB3 gene is linked to an increased risk of blood clots including stroke, heart attack, and DVT. But this variant also comes with a positive trade-off. Learn more with your genetic raw data.
C-Reactive Protein (CRP): Marker of Inflammation
Chronic inflammation is the driver of many common diseases such as heart attacks, diabetes, obesity, and autoimmune diseases. C-Reactive Protein is a marker of inflammation. Genetic variants can increase or decrease CRP levels.
Prothrombin: Blood Clot Risk
Genetic variants in the prothrombin gene increase the risk of blood clots (DVTs). Learn if you carry this risk factor for miscarriage, blood clots, and stroke.
Factor V Leiden Gene
The factor V Leiden genetic mutation significantly increases the lifetime risk of blood clots. Check your genetic data to see if you carry this mutation – and then learn to recognize the symptoms of blood clots.
HDL Levels Can Be Genetic
HDL cholesterol levels are considered to be about half due to genes with the rest due to diet, infection, etc. Learn more about the genetic variants that influence HDL cholesterol and how it affects heart health.
Heart Health Topic Summary
Utilize our Heart Health Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)
Interaction between high-fat diet, blood pressure, and your genes
Wondering if you should cut down on red meat and fat to lower your blood pressure? According to a new study, it could depend on your genes.
Coffee: Is it right for your genes?
Wondering how your genes influence your reaction to coffee? Find out if you will benefit from drinking coffee and how this interacts with your genes. (Member’s article)