The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
The FTO gene is nick-named the ‘fatso gene’ because of its association with obesity. This article digs into the current research on the FTO gene and then will give you some science-based options for controlling your weight if you carry the FTO genetic variant.
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Explore the complexities of PCOS, including symptoms, hormonal dysregulation, and the role of genetics. Learn how to target individual pathways.
There are several key players in our body’s regulation of hunger, satiety, and energy expenditure. Leptin and ghrelin are two pivotal hormones involved in our desire to eat. Within that leptin pathway, another key regulator of our body weight is MC4R. (Member’s article)
Are you naturally a short sleeper? Mutations in the DEC2 gene decrease the need for sleep.
Take a look into the science of the lingering effects of viruses, including chronic fatigue syndrome and long-haul viruses.
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
The hunger hormone, ghrelin, is important in appetite regulation and satiety. Learn how your genes interact with your diet when it comes to ghrelin levels. (Member’s article)
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
PPARδ is a key player in how and when your muscles burn fat for fuel. Genetic variants in the PPARD gene impact how well your muscles utilize fatty acids. These variants also impact how much of a fat-burning benefit you get from exercise.
Genetic variations play a role in how people react to carbohydrates in the diet. Learn about a few genes that affect insulin or glucose levels based on carbohydrate consumption. Use your genetic raw data and discover how your body handles carbohydrates.
Genetics plays a huge role in how an individual responds to a vaccine. Learn more about vaccines, immunity, and genetic variants that affect the response.
An overview explaining how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes. Start here and then dive deeper into the specific topics.
The APOE gene variants are linked with the risk of Alzheimer’s disease. Find out whether you carry the APOE risk type for Alzheimer’s – and learn what research shows about supplements and lifestyle changes to prevent this disease.
Your circadian rhythm influences your immune response. Learn how this rhythm controls white blood cell production and why melatonin protects against viral and bacterial infections.
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
Your vitamin D levels are impacted by sun exposure and your genes. Learn more about how vitamin D is made in the body and how your genetic variants impact your levels.
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.