HPA Axis Dysfunction: Genes and Environment

Stress. We all face it at times! But it doesn’t affect us all the same way.  Some people bounce back easily from a stressful situation. Others may face the effects of stress continually over their lifetime. I’m going to dig into the science of how…

Genetic Variants Associated with PCOS

Polycystic ovarian syndrome (PCOS) is an endocrine disorder that causes an increase in androgen hormone production in women. It affects 5 -10% of premenopausal women, and genetics plays a large role in whether you have PCOS. There is no one gene that causes PCOS, but…

Resilience: Genetic Variants Involved in Surviving Childhood Trauma

Exposure to childhood trauma, such as exposure to abuse, violence, or repeated stress, can have a long-lasting effect. Adults who were exposed to childhood trauma have higher rates of depression, PTSD, suicide, and anxiety disorders. The question that researchers have attempted to answer is: Why…

How do your genes influence testosterone levels?

While bodybuilding and athletes may come to mind with the word testosterone, it is actually an important hormone for both men and women. In men, low serum testosterone levels are linked to an increased risk of metabolic syndrome, type-2 diabetes, atherosclerosis, and heart disease…

Thyroid Hormone Levels and Your Genes

The thyroid is a master regulator of many of your body’s systems. It is integrally involved in metabolism and helps maintain body temperature, heart rate, breathing, and body weight. The thyroid is a butterfly-shaped gland that is located at the front of your throat…

PMS, Genetics, and Solutions

A lot of women know the moodiness and brain fog that comes with premenstrual syndrome (PMS).  It can range from simply feeling irritable and icky to being something that really interferes with our lives. What role do genes play in PMS?  It has been shown…

COMT – A gene that affects your neurotransmitter levels

COMT gene function: The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine, and norepinephrine. This enzyme adds a methyl group from SAMe to the dopamine, epinephrine, or norepinephrine molecules, thus changing them into a different substance. COMT is also…