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HMGB1 gene: inflammatory response protein important in sepsis and COVID-19

The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.

Vitamin D, Genes, and Your Immune System

Vitamin D is more than just a ‘vitamin’. It is actually a hormone essential to many processes in your body – including your immune system. Learn how vitamin D helps the immune response to coronavirus, flu, and other respiratory viruses.

9 Genes that Impact the Response to Vaccines

Genetics plays a huge role in how an individual responds to a vaccine. Learn more about vaccines, immunity, and genetic variants that affect the response.

Acute Respiratory Distress Syndrome Genes

ARDS is caused by an overwhelming immune response to a virus, bacteria, or lung injury. Learn more about which of your immune system genes are involved in ARDS.

Acne: Root Causes & Personal Solutions

Acne is thought to be 80% heritable. Learn how your genetic variants increase your risk of acne and find specific solutions that work for those genetic pathways.

C-Reactive Protein (CRP): Marker of Inflammation

Chronic inflammation is the driver of many common diseases such as heart attacks, diabetes, obesity, and autoimmune diseases. C-Reactive Protein is a marker of inflammation. Genetic variants can increase or decrease CRP levels.

Are you allergic to grass pollen? It may be genetic.

Allergies are usually due to a mix of genetic susceptibility and being exposed to certain triggering molecules. Several different gene variants have ties to an increased risk of grass pollen allergies.

Increased Inflammation and IL-17A Genetic Variants

Some people have a more sensitive immune system and are more prone to inflammatory reactions. We need a balance in the body between fighting off pathogens and not having too much of an inflammatory response. Learn more about what triggers inflammation and how your genes play a part.