Can you get the COVID vaccine if you have MTHFR?
Is the MTHFR mutation is a reason not to get the covid vaccine? Learn more with a look into the research behind MTHFR mutations and vaccines.
Inflammation and Immune Response
Genetic variants influence our immune response, affecting both our ability to combat pathogens and our susceptibility to chronic inflammation. For example, we are all unique in our response to different pathogens. Certain variants in inflammatory cytokine genes, such as TNF-alpha, may increase susceptibility to chronic inflammatory conditions while at the same time increasing your ability to fight off specific viruses or bacteria.
You can use your genetic data to understand which pathways are likely involved for you, and then use the lifehacks sections to discover the right solution for your genes.
Where to start?
Summary Reports for Members:
| Inflammation Summary | Immune System Summary Report |
Latest articles about Inflammation and Immune Health:
COVID-19 & Genetics: Who gets sick and why?
Not everyone gets sick when exposed to the SARS-CoV-2 virus. While there are many factors that come into play here, research points to genetics as playing a role. Several good genetic studies have recently been released showing which genes are important in COVID-19 susceptibility. Learn more and check your genes.
How to Check Your Genetic Data for G6PD Deficiency
People who carry the genetic mutations that cause G6PD deficiency are at an increased risk for hemolytic anemia when taking quinine-based medications. This article is intended to be a ‘heads up’ for anyone who is considering using quinine or chloroquine without a doctor’s advice for COVID-19.
IL-17: Chronic Inflammation & Autoimmune Risk with IL17A, IL17F
The IL17 gene codes for an important part of the immune system. When it is overactive, IL-17 can contribute to the risk of autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease.
FUT2: Check to See if You Are a Secretor or Non-Secretor
A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This alters the gut microbiome – and protects you from Norovirus.
Inclusion Body Myositis: Genomics and Solutions
Inclusion body myositis is a progressive, chronic condition that causes muscle weakness. It may be an interplay between inflammation, the dysregulation of proteins, mitochondrial dysfunction, and changes to autophagy. Somewhere in the mix, autoimmunity may be triggering it.
HMGB1 gene: inflammatory response protein important in sepsis and COVID-19
The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.
Vitamin D, Genes, and Your Immune System
Vitamin D is more than just a ‘vitamin’. It is actually a hormone essential to many processes in your body – including your immune system. Learn how vitamin D helps the immune response to coronavirus, flu, and other respiratory viruses.
Tinnitus and Meniere’s Disease: Genetic Susceptibility to Ringing in Your Ears
Genetics plays a role in both Meniere’s disease and tinnitus. Understanding your genetic susceptibility may help point you to the right solutions.
9 Genes that Impact the Response to Vaccines
Genetics plays a huge role in how an individual responds to a vaccine. Learn more about vaccines, immunity, and genetic variants that affect the response.
Kawasaki Disease: Inflammatory disease in children due to pathogens
Kawasaki disease is an excessive inflammatory response that some children have due to viral or bacterial illnesses. Several genetic variants are tied to an increased susceptibility to Kawasaki disease.
Chronic Sinus Infections: Genetics, Reasons, Solutions
Genetics plays a role in the likelihood of having chronic sinus problems. This article looks at the genetic reasons driving some people to have chronic sinus infections.
Acute Respiratory Distress Syndrome Genes
ARDS is caused by an overwhelming immune response to a virus, bacteria, or lung injury. Learn more about which of your immune system genes are involved in ARDS.
Circadian Rhythm and Your Immune Response to Viruses
Your circadian rhythm influences your immune response. Learn how this rhythm controls white blood cell production and why melatonin protects against viral and bacterial infections.
Genetic Susceptibility to Viruses
Viral immunity-your genes protect you. Your genetic variants shape your immune system and give you superpowers against some pathogens, perhaps more susceptible to others.
Gingivitis: The Genetic Connection between Gum Disease, Inflammation, and Overall Health
You brush, you floss, and your gums still bleed… perhaps you carry some of the genetic variants associated with gingivitis? Check your genetic data to see. (Member’s article)
Acne: Root Causes & Personal Solutions
Acne is thought to be 80% heritable. Learn how your genetic variants increase your risk of acne and find specific solutions that work for those genetic pathways.
C-Reactive Protein (CRP): Marker of Inflammation
Chronic inflammation is the driver of many common diseases such as heart attacks, diabetes, obesity, and autoimmune diseases. C-Reactive Protein is a marker of inflammation. Genetic variants can increase or decrease CRP levels.
Leveraging your Gut Microbiome to Change your Gene Expression
Learn how your gut microbiome influences the expression of your core circadian rhythm genes.
Genetic Variants that Increase Susceptibility to Lyme Disease
Lyme disease recovery can vary. Whether you recover quickly or have chronic symptoms that include joint pain or arthritis, it may be due to the genetic variants that you carry.
Are you allergic to grass pollen? It may be genetic.
Allergies are usually due to a mix of genetic susceptibility and being exposed to certain triggering molecules. Several different gene variants have ties to an increased risk of grass pollen allergies.
Increased Inflammation and IL-17A Genetic Variants
Some people have a more sensitive immune system and are more prone to inflammatory reactions. We need a balance in the body between fighting off pathogens and not having too much of an inflammatory response. Learn more about what triggers inflammation and how your genes play a part.
Research studies on histamine intolerance and mast cells
Histamine plays several important roles in the body. Learn more about the newest research into histamine intolerance and mast cells.