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COVID-19 & Genetics: Who gets sick and why?

Not everyone gets sick when exposed to the SARS-CoV-2 virus. While there are many factors that come into play here, research points to genetics as playing a role. Several good genetic studies have recently been released showing which genes are important in COVID-19 susceptibility. Learn more and check your genes.

Blood clots, platelets, and adenoviruses

Take a look into the role of platelets, their connection to blood clots, and a discussion of the research on adenovirus-vector therapy, thrombocytopenia, and platelet reactions.

G6PD Deficiency: How to check your genes

People who carry the genetic mutations that cause G6PD deficiency are at an increased risk for hemolytic anemia when taking quinine-based medications. This article is intended to be a ‘heads up’ for anyone who is considering using quinine or chloroquine without a doctor’s advice for COVID-19.

CBD Oil: Will it work for you?

Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.

FUT2: How to check if you are a secretor or non-secretor?

A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This alters the gut microbiome – and protects you from Norovirus.

Inflammation Summary Report

Utilize our Immune and Inflammation Topic Summary Reports with your 23andMe or AncestryDNA genetic data to discover the articles most relevant to you. These summaries distill the complex information down into just a few words. Please refer to the linked articles for details and complete references. (Member’s article)

HMGB1 gene: inflammatory response protein important in sepsis and COVID-19

The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.

Vitamin D, Genes, and Your Immune System

Vitamin D is more than just a ‘vitamin’. It is actually a hormone essential to many processes in your body – including your immune system. Learn how vitamin D helps the immune response to coronavirus, flu, and other respiratory viruses.

9 Genes that Impact the Response to Vaccines

Genetics plays a huge role in how an individual responds to a vaccine. Learn more about vaccines, immunity, and genetic variants that affect the response.

Acute Respiratory Distress Syndrome Genes

ARDS is caused by an overwhelming immune response to a virus, bacteria, or lung injury. Learn more about which of your immune system genes are involved in ARDS.

Genetic susceptibility to viruses

Viral immunity-your genes protect you. Your genetic variants shape your immune system and give you superpowers against some pathogens, perhaps more susceptible to others.​

Chronic Inflammation & Autoimmune Risk: IL17 gene variants

The IL17 gene codes for an important part of the immune system. When it is overactive, IL-17 can contribute to the risk of autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease.