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Genetic variants that affect Heat Shock Proteins Reasons to upregulate and downregulate heat shock proteins

Heat Shock Proteins: Cellular Resilience

Heat shock proteins are activated by cells in response to a stressful condition, such as exposure to high heat. Learn more about the essentials of heat shock proteins, including how to activate them and the genetic variants that impact how well they work.

Opioid Receptor Genetic Variants and Addiction

Opioid Receptors Genetic Variants and Addiction

Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)

Digesting Carbohydrates: Amylase (AMY1 Gene)

Digesting Carbohydrates: Amylase variants

Carbohydrate digestion begins in the mouth with an enzyme called amylase. Take a look into how the amylase enzyme works, genetic variants that impact your production of amylase, and solutions if you are low in amylase.

Do you wake up at 4 am? Genes and early waking insomnia

Seeing 3:30 or 4:00 on your clock each morning? There could be a physiological reason for this. Learn about the genetic variants linked to early waking insomnia and the connection to depression. (Member’s article)

Genetic Variants that Impact Testosterone Levels, SHBG gene, FAM9B gene, FSHB gene, and LIN28B gene. The effect of Microplastics on testosterone

Testosterone: Genetic Variants that Impact Testosterone Levels

While diet and lifestyle play a role in testosterone levels, in males, there is a strong genetic component as well. Check out your genes to see if they are playing a role in your low T levels — and then check out the Lifehacks.

Circadian Rhythm Genes, CLOCK gene, PER1 family of genes

Circadian Rhythm Genes: Our Internal Clocks

The body’s circadian clock regulates many different functions over the course of a 24-hour day. The genes that code for different parts of the circadian clock have a wide-ranging effect on sleep, mood, and overall health.

Vitamin B6 deficiency genes, foods high in vitamin B6

Vitamin B6: Genetics, Absorption, and Deficiency

Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.

miRNAs control gene expression by blocking translation of mRNA into the protein.

miRNA: What It Is and How It Works

miRNAs are small non-coding RNA molecules that regulate gene expression. They are important for healthy aging, longevity, metabolic health, and immune function.

New research on FTO gene variants, FTO and heart disease, viral susceptibility

FTO and m6A Methylation

Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.

SIRT3 gene variants, Aging, longevity, and Mitochondrial Function

SIRT3, Aging, and Mitochondrial Function

How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.