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Leptin: The Satiety Hormone Resetting Leptin Sensitivity

Leptin Receptors: Genetics and Hunger

Do you wonder why other people don’t seem to struggle with wanting to eat more? Leptin is a hormone that signals to the brain when you are full and should stop eating. Genetic variants in the LEPR gene are linked to obesity and desire to eat more.

PRO: Supplement Research Connections

Pro Member resource guide to help navigate popular supplements concerning genetic variants and health topics. You will find links to all corresponding articles to help you narrow down areas of interest.

Leaky Gut Genes: Emulsifiers in Processed Foods

Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.

LDL cholesterol genes, natural supplements to lower cholesterol

LDL Cholesterol: Genetics, Personalized Solutions

Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.

News and Research: Boosting GABA with probiotic

Discussion of a published study that looked at over a thousand different Bifidobacteria strains, investigating how they interact with their host (e.g., you and I).

MTHFR, Folate, and Fertility

Folate Optimization: MTHFR and Fertility

MTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.

Melatonin: Key to Health and Longevity, melatonin synthesis pathway

Melatonin: Key to Health and Longevity

More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.

Nutrigenomics and the SNPs related to zinc, inflammation, and diabetes

Zinc genes: The healing power of zinc

Learn why zinc is important for your immune system and so much more. Find out how your genes impact your need for zinc and discover ways of boosting your zinc status. 

Supplemental Melatonin: Immune Response and Inflammation

Research studies on melatonin and SARS-CoV-2

The research on melatonin shows that it plays an important role in our body’s inflammatory response to pathogens. Learn more about the current research on melatonin for COVID-19 and the science behind how it impacts immune response.

Ghrelin: The Hunger Hormone, genetic variants that impact ghrelin, circadian rhythm impact on ghrelin

Ghrelin: The Hunger Hormone

The hunger hormone, ghrelin, is important in appetite regulation and satiety. Learn how your genes interact with your diet when it comes to ghrelin levels. (Member’s article)

MTHFR mutations explained, frequency of C677T SNP, A1298C SNP, Supplement Interaction, MTHFR variant risks

MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

Sleep Report: Genetic Causes of Sleep Problems

This is a quick (Member’s Only) overview of how your genetic variants impact various aspects of sleep including insomnia, circadian rhythm, and sleep quality.

Past Newsletters

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FASD1 and FASD2 genes, converting Omega 3&6 in DHA and EPA

FADS1 and FADS2: Omega-3 and Omega-6 Fatty Acids

We all vary in how well we convert the plant-based omega-3 oils into the DHA and EPA that our body needs. Some people are really poor at this conversion and thus should either eat more fish or consider taking a DHA / EPA supplement. Learn more about how your variants might affect your health.