Pyruvate Dehydrogenase is central to cellular energy production. Learn about its role in energy production, genetic mutations, association with ME/CFS and Long Covid, and strategies to manage its deficiencies.
Red and near-infrared wavelengths of light interact with mitochondria to produce ATP. Learn why – and discover how mitochondrial genes may play a role.
Biotin, also known as vitamin B7 or vitamin H, is a cofactor that aids in the metabolism of fats, carbohydrates, and proteins. Biotin deficiency due to diet is pretty rare, but there are genetic variants that can increase your risk for biotin deficiency or insufficiency.
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine.
CoQ10, or ubiquinone, is an integral part of mitochondrial energy production. It is also used as a lipid-soluble antioxidant. Learn how age and genes affect it.
Supplementing with Alpha-ketoglutarate (αKG) might be beneficial for longevity since it plays a role in energy production and inflammation reduction.
Riboflavin, or vitamin B2, is an essential cofactor for many biological pathways. Learn how to check your genetic raw data to see if you may need more riboflavin.
How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.
Trying to get pregnant? Healthy eggs are vital for a successful pregnancy. Discover four key ways to improve your egg quality, according to research studies.
MS susceptibility is linked to both genetic causes and environmental factors. Learn how those two combine – and possible solutions.
Essential tremor (ET) is a neurological disease causing involuntary shaking in places of the body while performing tasks such as writing or eating. Learn more about this disease and discover the genetic causes of ET.
Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.
Five quick examples of how you could use your genetic data to dial in the supplements worth trying and which ones to skip for now.
Arsenic exposure occurs via well water, in certain foods, and through breathing. This article covers the pathways the body uses to get rid of arsenic, and it includes information on genetic variants that may impair the detoxification of arsenic.
Nootropics are supplements used to boost cognition and memory. Learn how the substance works and the genes connected to the mechanism of action.
Heat shock proteins are activated by cells in response to a stressful condition, such as exposure to high heat. Learn more about the essentials of heat shock proteins, including how to activate them and the genetic variants that impact how well they work.
The FTO gene is nick-named the ‘fatso gene’ because of its association with obesity. This article digs into the current research on the FTO gene and then will give you some science-based options for controlling your weight if you carry the FTO genetic variant.
Some people have more active ‘internal heat’ and they actually are burning off more energy all the time. The UCP1 gene is important for mitochondrial energy use and heat production from brown fat. Genetic variants in UCP1 can cause weight gain and obesity.
How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
Take a look into the science of the lingering effects of viruses, including chronic fatigue syndrome and long-haul viruses.
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
The SCD1 enzyme converts saturated fatty acids to unsaturated fats. Learn how your genes impact this enzyme, and how this relates to weight loss.
The SIRTfood diet, made popular by Adele’s recent weight loss, theoretically works by affecting your sirtuin gene expression. Learn about your SIRT genes and your genetic variants.
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.