Weight Loss

Weight Loss Genetics – DHEA

Dehydroepiandrosterone (DHEA) is a natural steroid that  tends to peak around age 25 and drop off rapidly in older people.This steroid is secreted by the adrenal cortex, and it is involved in a lipid (fat) catabolism.  Some studies have shown that DHEA reduces fat accumulation in mice fed a high fat Read more…

By genelife, ago
Weight Loss

Weight Loss Genetics – PLIN1

The perilipin 1 gene codes for the protein that covers lipid droplets in fat cells.  This coating protects the lipid droplets from the enzymes that break down fats for use as energy in the body.  Increased perilipin is associated with obesity.  Mice bred to be deficient in perilipin eat more than Read more…

By genelife, ago
Weight Loss

Weight Loss Genetics – PPARG polymorphisms

The PPARG (peroxisome proliferator-activated receptor gamma) gene has been associated with obesity, metabolic syndrome and risk for type-2 diabetes.  This gene is involved in the regulation of fatty acid storage and in glucose metabolism.  PPAR-gamma specifically is activated by omega-6 polyunsaturated fatty acids and regulates adipocyte differentiation. The most commonly Read more…

By genelife, ago


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