Underlying Cause(s) of Depression: Leveraging Your Genetic Data
Depression can have multiple physiological causes. This article ties together 9 separate articles on depression to simply your genetic search.
Search Results for: depression
Is Inflammation Causing Your Depression and Anxiety? The Science Behind the Link
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Depression, Genetics, and Mitochondrial Function
How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
Circadian Rhythm Disruption as a Root Cause of Depression
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
Agmatine: Neuropathic pain and mood
Acting as a neurotransmitter and neuromodulator, agmatine holds promise for neuropathic pain, depression, and brain function.
Lithium Orotate and Vitamin B12: Benefits for Mood and Cognitive Support
For some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12. But other people may have little to no response. The difference may be in your genes.
MTHFR, Depression, Anxiety, Symptoms and Treatment
We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.
Circadian Rhythm Genes: Mood Disorders
Circadian rhythm disruption can drive mood disorders. Learn more about the genes involved and the ways to normalize your circadian rhythm.
Saffron Extract: What does the research show?
Recent clinical trials show that saffron extract is as effective as standard medications in some people for ADHD, Alzheimer’s, major depressive disorder, and high cholesterol.
Bipolar Disorder, Depression, and Circadian Clock Genes
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.
Serotonin: How Your Genes Affect this Neurotransmitter
Serotonin is a neurotransmitter that is important in depression, sleep, and many other aspects of health. Learn how your genetic variants in the serotonin receptor genes impact their function.
The Interaction Between BDNF and Serotonin
Genetic variants in the BDNF and serotonin receptor genes combine to increase the risk of depression and anxiety. Learn more about BDNF and how these variants interact — and check your genetic data to see how this applies to you.
Dopamine Receptor SNPs: Addiction, Mood, ADHD, and Schizophrenia
Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.
Lion’s Mane: Cognitive function, nerve regeneration
Lion’s mane mushrooms have a long history of being used as a medicinal food for increasing energy, improving nerve function, and boosting brain power.
Naltrexone: LDN & Genetics
The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome. Learn how this opioid antagonist works on the immune system and how your genetics can play a part in its efficacy.
Breast Implant Illness: The Interplay of Genetics and Symptoms
What is Breast Implant Illness (BII)? Learn more about this illness, its research, and possible genetic connections to autoimmune conditions.
Familial Mediterranean Fever: Mimics fibromyalgia, arthritis, inflammation
Familial Mediterranean fever (FMF) is a genetic condition of inflammatory episodes that cause painful joints, pain in the abdomen, or pain in the chest. It is most often accompanied by a fever. FMF is often misdiagnosed as various pain-related conditions such as fibromyalgia, myofascial pain syndrome, or gouty arthritis.
IL-17: Chronic Inflammation & Autoimmune Risk with IL17A, IL17F
The IL17 gene codes for an important part of the immune system. When it is overactive, IL-17 can contribute to the risk of autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease.
CTLA4 Gene: Autoimmune Risk Factor
The CTLA4 gene codes for a protein that is important in the immune system. It acts as a checkpoint that can downregulate your immune system response. Genetic variants in the CTLA4 gene can increase your risk for several different autoimmune diseases. (Member’s article)
Rheumatoid Arthritis: Genetics, Root Causes, and Treatment Research
Rheumatoid arthritis is caused by an immune system attack on the joints, causing thickening and inflammation of the joint capsule. It is caused by a combination of genetic susceptibility and environmental triggers.
HLA-B27: Genetic Variant That Increases Susceptibility to Autoimmune Diseases
The HLA-B27 serotype is linked to an increased risk of several autoimmune diseases, including ankylosing spondylitis, psoriatic arthritis, and IBD.
TNF-alpha: Inflammation, Chronic Diseases, and Genetic Susceptibility
Discover the role of TNF-alpha in inflammation and its link to chronic diseases. Learn how genetic variants affect TNF-alpha levels and explore natural solutions for chronic inflammation.
ME/CFS: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (and Long Covid?) Genes
Take a look into the science of the lingering effects of viruses, including chronic fatigue syndrome and long-haul viruses.
Mast Cells: MCAS, Genetics, and Solutions
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Brain & Mood Summary Report
Utilize our Brain & Mood Topic Summary Reports with your 23andMe or AncestryDNA genetic data to discover the articles most relevant to you. These summaries distill the complex information down into just a few words. Please refer to the linked articles for details and complete references. (Member’s article)