How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Depression can have multiple physiological causes. This article ties together 9 separate articles on depression to simply your genetic search.
We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.
Acting as a neurotransmitter and neuromodulator, agmatine holds promise for neuropathic pain, depression, and brain function.
Serotonin is a neurotransmitter that is important in depression, sleep, and many other aspects of health. Learn how your genetic variants in the serotonin receptor genes impact their function.
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
Genetic variants in the BDNF and serotonin receptor genes combine to increase the risk of depression and anxiety. Learn more about BDNF and how these variants interact — and check your genetic data to see how this applies to you.
Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.
Seeing 3:30 or 4:00 on your clock each morning? There could be a physiological reason for this. Learn about the genetic variants linked to early waking insomnia and the connection to depression. (Member’s article)
Low levels of BDNF (Brain-derived neurotrophic factor) are linked to introversion, stress resilience, cognition, and depression levels. Discover ways to increase your BDNF levels and mitigate the problems associated with the BDNF gene variants. (Member’s article)
Phthalates are a type of chemical used as plasticizers to make plastics more pliable. There has been a lot of research on the endocrine-disrupting effects of phthalates. Your genetic variants may impact whether phthalates are a problem for you.
The SULT genes help with phase II detoxification of estrogens, neurotransmitters, certain carcinogens, and steroid hormones.
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
Melanopsin is the receptor for blue light. It is found in the retina, skin, adipose tissue, and blood vessels. Genetic variants can impact reaction to blue light.
Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Long Covid is the persistence of symptoms after having COVID-19. Learn more about the underlying causes and treatments backed by the newest research.