CYP2D6 gene and medication reactions
The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.
Genetic variants about in the enzymes that break down drugs and toxins. These genetic differences are why some medications don’t work well for certain people. Our reactions to toxicants, such as pesticides, also rely on our genes.
Explanation of Phase I and Phase II Detoxification
Member’s: Check out the Detoxification Topic Summary Report for a quick overview of all your genetic variants related to how you detox or metabolize different compounds.
The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.
Caffeine remains the most popular ‘drug’ of choice for a large percentage of the population. Genetics determines how quickly your body processes and eliminates caffeine and whether it is likely to make you jittery or anxious.
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)
BPA, a chemical found in some plastics, has been linked to a variety of health issues in people. Learn more about BPA and the research into genetic responses to this chemical.
The CYP3A family of genes is involved in metabolizing about half of the drugs on the market today. Check your genes to see if you carry variants that impact the speed at which you metabolize medications.
Many genetic variants have been studied for Gulf War Illness. Take a look into the research behind the illness and discover some possible solutions to help with symptoms.
Modafinil is being used as a nootropic drug that increases alertness and gives a sense of well-being — to some users. Like most drugs, individual results seem to vary. Discover if this could be a viable option for you.
Once toxins are initially broken down in the body, they must be converted to a water-soluble molecule in order to …