We break down toxins and medications using enzymes. Genetic variants in the genes encoding the detox enzymes are why some medications don’t work well for certain people. Our ability to break down toxicants, such as pesticides, also relies on our genes. Using your genetic data, you can find out which toxicants may be more of a problem for you.
Background Explanation of Phase I and Phase II Detoxification
Members: Start with the Detoxification Topic Summary Report for a quick overview of all your genetic variants related to how you detox or metabolize different compounds.
Is buying organic worth the extra cost? There isn’t a one-size-fits-all answer to that question. Pesticides that are sprayed on conventionally grown foods affect people differently. Some people carry genetic variants that decrease their ability to detoxify specific pesticides, others may be more resilient. This is Part Two in a multipart series on pesticide detoxification.
Caffeine remains the most popular ‘drug’ of choice for a large percentage of the population. Genetics determines how quickly your body processes and eliminates caffeine and whether it is likely to make you jittery or anxious.
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)
The CYP3A family of genes is involved in metabolizing about half of the drugs on the market today. Check your genes to see if you carry variants that impact the speed at which you metabolize medications.
Many genetic variants have been studied for Gulf War Illness. Take a look into the research behind the illness and discover some possible solutions to help with symptoms.
Modafinil is being used as a nootropic drug that increases alertness and gives a sense of well-being — to some users. Like most drugs, individual results seem to vary. Discover if this could be a viable option for you.
Utilize our Detoxification Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)
N-acetyltransferase is a phase II detoxification enzyme that gets rid of several types of toxicants. It helps your body eliminate aromatic amines, drugs, cigarette smoke, and carcinogens.