400+ in-depth articles with embedded genetic reports:
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Articles with Genotype Reports (by Publication Date)
- T Cell Exhaustion in Long COVID, ME/CFS, and Cancer: Mechanisms and Solutions
T cell exhaustion reduces immune function in chronic infections, long Covid, and cancer. Explore evidence-based natural interventions, and understand the mechanisms. - GLP-1 and Genetics: How Your Genes Affect Appetite, Insulin Response, and Weight Loss Medications
Learn how GLP-1 regulates appetite and insulin, plus how genetic variants affect your response to GLP-1 medications and natural GLP-1 alternatives. - Urolithin A for Mitochondrial Health and Muscle Function
Urolithin A supports mitochondrial function and muscle health. Discover how your gut produces it, who benefits most from supplements, and what the research shows. - PFAS, Your Genes, and Your Health: From Mitochondrial Function to Immune Response
PFAS are persistent “forever chemicals” found in everyday products that are used to make products water-resistant, stain-resistant, and non-stick. Research shows PFAS are associated with reproductive issues, immune suppression, thyroid dysfunction, and more. - Raynaud’s: Causes, Symptoms, and Genetics
Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility. - Trigger Points, Myofascial Pain Syndrome, and Underlying Causes
Trigger points are hyperirritated knots in the muscle and fascia that can refer pain to a nearby region of the body. - Risk of Osteonecrosis from Bisphophonates
A small percentage of people taking bisphosphonates will experience osteonecrosis – bone death – in the jaw. Genetic variants are part of the susceptibility. - Neuropilins: Neurodevelopmental Disorders, Gut Barrier, & Covid Brain
Neuropilins act as receptors and are found on the surface of cells. Learn about its many roles body, such as in the immune, vascular and nervous systems. - BPC-157: Tendon Repair and More
BPC-157 (body protection compound-157) is a peptide derived from human gastric juice that is 15 amino acids in length. Studies show that it promotes the healing of different tissues, including skin, muscle, bone, and tendons. - Trace Minerals and Neurocognitive Optimization
Trace minerals affect neurotransmitter levels and neuroinflammation. Getting the right levels of micronutrients can help optimize neurocognitive function. - Thymosin Beta 4: Genetics & Supplemental Peptides
Thymosin beta 4 is a natural peptide that is made in the body and helps with wound healing, muscle recovery, and decreasing inflammation. It is also available as a supplemental peptide. - ABCB1 (P-glycoprotein): Response to Medications, HRT, and Environmental Toxins
ABCB1 encodes P-glycoprotein, a transporter that removes toxins – and medications – from the body. Genetic variants in the ABCB1 gene can affect how well a medication works for you. - Minerals and Micronutrients Topic SummaryBookmarkPlease see the linked articles for details and complete references. Bookmark
- Molybdenum: Genetic Connections, Sulfur Metabolism, and Cofactor Deficiency
Molybdenum is a trace mineral needed in the right amounts for sulfur detoxification and the formation of uric acid. - APOB gene: Apolipoprotein B Levels and Health Risks
ApoB is a better predictor of heart disease risk than LDL-C or total cholesterol. Genetic variants can increase or decrease ApoB levels. - Very Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD)
VLCAD deficiency causes the mitochondria to be unable to use long-chain fatty acids for energy production. This can result in hypoglycemia or mitochondrial dysfunction. - Hypnosis Genes: Genetic Influences on Hypnosis
Not everyone is equally susceptible to hypnosis. Learn how your genetic variants play a role in how your brain focuses and responds to hypnotic suggestions. - Lactate, Lactate Dehydrogenase, and Lactate Transporters
Lactate is much more than a workout byproduct—it’s a key energy source, signaling molecule, and regulator of metabolism, brain health, and disease. - Polycythemia Vera: Understanding Inherited and Somatic Mutations behind This Rare Blood Disorder
Polycythemia vera: See how your genetics and environment contribute to this rare blood disorder. Understand the causes, risks, and role of inheritance. - Oxalates: What Your Genes and Diet Say About Oxalate Health Issues
Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it. - Cordyceps: Clinical Trials, Mechanism of Action, and Genetic Connections
Cordyceps mushroom extract has immunomodulatory and anti-inflammatory effects. Studies show benefits for asthma, resistance training, endurance training, and kidney disease. - Specialized Pro-resolving Mediators (SPMs): The Resolution of Inflammation
Chronic inflammation is at the root of all diseases. New research discusses how pro-resolving mediators are the key to the resolution of inflammation. - Epstein-Barr Virus: Genetic Risks, Reactivation, and Chronic Illnesses
Epstein-Barr virus (EBV) impacts lifelong health, links to autoimmune diseases, genetic risk factors, and practical steps to reduce reactivation. - Snoring: Genes and Solutions
Genetics plays a role in snoring —certain genes affect airway structure, fat distribution, and muscle control. - Problems sleeping? Your genes can point to individualized solutions
Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes. - Mast Cells: MCAS, Genetics, and Solutions
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances. - FOLR1 and FOLR2: Transporting Folate, Folinic Acid, and Folic Acid into Cells
Genetic variants in the FOLR1 and FOLR2 genes (folate receptors alpha and beta) can impact folate in the brain and in the immune response. - Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health
Learn how carnitine powers cellular energy, supports organ health, and influences metabolism. Discover its benefits for brain, liver and immune function, plus how genetics affect your carnitine needs. - Histamine Intolerance: Genetic Report, Supplements, and Real Solutions
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance. - Pregnancy: How Your Genes affect the Nutrients You Need
Pregnancy is a time of increased nutritional needs, and your genes can help you dial in your diet to prevent nutrient deficiencies. - Reelin – Long Covid, Depression, and Alzheimer’s
Reelin is a key glycoprotein involved in brain development, cognition, and neurodegenerative diseases like Alzheimer’s, schizophrenia, autism, and cardiovascular health. - FTO and m6A Methylation
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease. - Methylene Blue: Genetic Connections and Research Studies
Methylene blue has neuroprotective and anti-inflammatory properties, but it isn’t for everyone. Learn about the genetic variants that throw a caution flag on this one. - Casein and Cow’s Milk Allergies
Cow’s milk allergy can be due to your immune system responding to casein or β-lactoglobulin. Genetic variants in immune-system genes increase susceptibility – along with environmental factors. - Thiamine: Genomics, Cellular Energy, and Cognitive Function
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine. - Glutamate Receptors and Transporters
Glutamate transporters and receptors carefully balance glutamate levels in the brain. Variants in the glutamate genes can affect how your brain balances glutamate. - Building Up Iron: Hemochromatosis Mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations. - miRNA: What It Is and How It Works
miRNAs are small non-coding RNA molecules that regulate gene expression. They are important for healthy aging, longevity, metabolic health, and immune function. - Elevated Fibrinogen: Risk factor for blood clots
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level. - Opioid Receptors Genetic Variants and Addiction
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article) - Resveratrol: Studies, Genetic Interactions, and Bioavailability
Resveratrol is a polyphenol with anti-inflammatory and antioxidant properties. Studies show that it affects heart health, bone health, cognitive function, and metabolic health. - Migraine Solutions Tailored to Your Genes: Triggers, Treatments, and Tools
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA. - Microplastics Research Roundup
Microplastics research shows that these microscopic bits of plastics are a real problem for health and wellness. - BPA and BPS: How Your Genes Influence Bisphenol Detoxification
BPA, a chemical found in some plastics, has been linked to a variety of health issues in people. Learn more about BPA and the research into genetic responses to this chemical. - Resistance Training Genetics: Personalized Muscle Building
Learn how genetics and lifestyle factors influence muscle growth from resistance training. Covers the science behind strength gains, from molecular pathways to genetic applications backed by research. - Glutamate: Synthesis, transport, and supplement interactions
Glutamate is synthesized from glutamine or alpha-ketoglutarate. Imbalanced glutamate levels play a role in several neurological disorders. - BPIFB4 Gene: Linked to Longevity and Heart Health
Discover the impact of the BPIFB4 gene on longevity and immunity, and find out if you have the longevity variant in your genotype report. - Vitamin K: Bone Strength, Blood Clots, Calcification, and Genetics
Genetic variations cause people to have higher or lower levels of vitamin K, which can affect blood clotting. Learn more about the genes that affect vitamin K and how it relates to your genetic raw data. - PCSK9: Cancer Recurrence & Prevention
Lower PCSK9 levels have been shown in research studies to correlate to a significantly reduced risk of metastatic recurrence in certain types of cancer. - Flu Season: Genetics and Your Immune Response
Are you more genetically susceptible to the flu? Learn how your genes play a role and discover research-backed natural options to beat the flu. - Medium Chain Acyl-CoA Dehydrogenase Deficiency: Check your genetic data
Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is an “inborn error of metabolism” which impairs the body’s ability to break down medium-chain fatty acids for fuel. Learn more about this metabolic disorder. - MTHFR Mutation: What is it? How to check your raw data.
The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants. - Testosterone: Genetic Variants that Impact Testosterone Levels
While diet and lifestyle play a role in testosterone levels, in males, there is a strong genetic component as well. Check out your genes to see if they are playing a role in your low T levels — and then check out the Lifehacks. - Atrial fibrillation: Intersection of genetic susceptibility with inflammation and remodeling
Atrial fibrillation is an irregular heartbeat in the atrium. Genetic variants combine with inflammation and environmental triggers in causing A-fib. - Hidradenitis Suppurativa: Genetic Causes and Possible Solutions
Hidradenitis suppurativa is caused by overactive inflammation and hyperkeratosis. Genetics plays a big role – along with environmental factors. - Vitamin B12, MTR & MTRR, and Methylation
There are several genes that can influence your absorption, transport, and need for vitamin B12. Some people need higher amounts of B12, and some people thrive on different forms of B12. Take a look at your genetic data to see if you should up your intake of B12. - Gut Mucosal Barrier: Foundational and Underappreciated
Your gut mucosa protects you from microbes in the gut, your own digestive enzymes, and toxins from the environment. Learn what you can do to keep your gut mucosal barrier healthy. - Supplements with Genetic Connections
Linking supplements and genetic SNPs so that you can more easily find out what may work for you – and what to be cautious about. - Glutathione: Master Antioxidant, Reducing Oxidative Stress, and Detoxification
Glutathione is an antioxidant produced in all cells to balance out ROS. Genetic variants can impact your glutathione levels, which can alter your ability to detoxify certain substances or withstand stressors in the body. - How to Shift Your iPhone Screen to Red at Night
Learn how to shift your iphone screen to be completely red at night (no blue light) with a triple-click of the power button.