Blood-Brain Barrier Genes: SNPs, Leaky BBB Risks & Solutions
Genetic variants can increase susceptibility to blood-brain barrier (BBB) dysfunction. This can increase the risk of Alzheimer’s, ADHD, and mood disorders.
Genetic variants can increase susceptibility to blood-brain barrier (BBB) dysfunction. This can increase the risk of Alzheimer’s, ADHD, and mood disorders.
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Explore how neuropilin variants shape neurodevelopment, vascular permeability, gut barrier function, viral entry (SARS‑CoV‑2, EBV, CMV), and risks for autoimmunity and cancer.
Glutamate, the main excitatory neurotransmitter, is tightly regulated through synthesis, transporters, and GABA balance, with genetic variants influencing risk for migraines, OCD, seizures, and schizophrenia.
There are several genes that can influence your absorption, transport, and need for vitamin B12. Some people need higher amounts of B12, and some people thrive on different forms of B12. Take a look at your genetic data to see if you should up your intake of B12.
The thyroid is a master regulator controlling many of your body’s systems. It is integral for metabolism and body temperature. Learn about specific thyroid-related variants.
Discover the complex interplay of genetics and environment in ADHD susceptibility. Learn how circadian rhythm and neurotransmitter genes contribute to the disorder, and how toxicant exposure may increase risk.
Brain fog has many roots: nutrient deficiencies, hypoxia, inflammation, viral infections, microclots, histamine, amino acid metabolism, and genetics — plus targeted strategies to restore clear thinking.
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Long Covid is the persistence of symptoms after having COVID-19. Learn more about the underlying causes and treatments backed by the newest research.
Understand the connection between statin use and brain fog. Dive into the research on how cholesterol-lowering drugs impact cognitive health and memory.
Your APOE and COMT genotypes together may impact memory and cognitive function in older age.
The interesting thing about Lyme disease is that the genetic variants you carry impact both how the disease affects you and how well antibiotics work for you. Learn whether your genetic variants are linked to post-treatment Lyme disease symptoms such as joint pain. (Member’s article)
Nickel allergy: Explore how genes, everyday exposures, and diet contribute to nickel sensitivity, including rashes, GI symptoms, and brain fog.
New research suggests the benefits of luteolin (a flavonoid found in fruits, vegetables, and herbs) may include anti-inflammatory and neuroprotective properties.
We have many systems in place to control blood pressure and heart rate. The ADRA1A receptors are part of this system. Discover how variants can influence blood vessel stress response and how others are connected to cognitive changes.
What is Breast Implant Illness (BII)? Learn more about this illness, its research, and possible genetic connections to autoimmune conditions.
Discover the research and genetic links to why you may be more susceptible to certain outcomes with long spike.
Pernicious anemia is a B-12 deficiency anemia caused by an autoimmune attack on the cells that produce intrinsic factor. Learn how genes impact susceptibility to pernicious anemia.
Nootropics are supplements used to boost cognition and memory. Learn how the substance works and the genes connected to the mechanism of action.
Explore the genetic basis of POTS, from HLA and norepinephrine transporter variants to EDS, MCAS, and long Covid connections, plus strategies to better manage symptoms.