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MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

COMT: How to Optimize Your Supplements for Your COMT Genotype

Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.

Folate Optimization: MTHFR and Fertility

MTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.

Blood pressure, MTHFR, and riboflavin

The common MTHFR C677T variant increases the relative risk of high blood pressure. Learn how to add more Riboflavin (B2) into your diet to reduce risk.

Sudden Hearing Loss: Viruses, Vaccines, and Genes

Genetic variants can significantly increase your risk of sudden sensorineural hearing loss. Learn more about the current research on sudden sensorineural hearing loss, including links to viral and vaccine causes.

Genetic Causes of Male Infertility

Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.

FTO is more than just an obesity gene

FTO and m6A methylation: From COVID to Cancer to Obesity

The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.

MTHFR: Going Beyond C677T and A1298C

The MTHFR C677T and A1298C variants get a lot of press, but they do not give the whole picture of the MTHFR gene. Additional variants are impacting the functionality of the enzyme.

Depression genes

Depression, genetics, and mitochondrial function

How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.

MTHFR, depression, anxiety, symptoms and treatment

We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.

woman with pregnancy test in hand

Genetic links to infertility for women

Your genes may be playing a role in your infertility — and knowing which genetic variants you carry may help you figure out solutions to try.

MTHFR and Migraines

The MTHFR C677T variant increases the risk of migraines. Learn how to check your genetic data and how to mitigate the risk.

Nitric Oxide Synthase (NOS3): Heart health, blood pressure, and healthy aging

Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.

Dads matter: MTHFR variants in fathers affect miscarriage risk

Dads matter – in conception, pregnancy, and throughout life. It is easy to see how prospective moms need to clean up their diets, exercise, and sleep well before getting pregnant, but recent studies show that a dad’s MTHFR variants also affect infertility and miscarriage risk.