TNF-alpha is a key inflammatory cytokine linked to autoimmune, cardiovascular, mood, and neurodegenerative diseases. Learn how TNF gene variants affect your risk and potential natural TNF inhibitors.
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
Do your fingertips turn white and blue when cold? Discover the causes and symptoms of Raynaud’s syndrome and your genetic susceptibility.
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Mycotoxins from food and water-damaged buildings are cleared via CYP450, GST, and UGT pathways. Variants in these detox genes explain why mold and mycotoxin sensitivity varies.
Cordyceps mushroom extract has immunomodulatory and anti-inflammatory effects. Studies show benefits for asthma, resistance training, endurance training, and kidney disease.
The resolution of inflammation is an active process that depends on lipid mediators, called specialized pro-resolving mediators (SPMs).
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
Glyphosate is the active ingredient in the herbicide Round-Up. A recent study showed that people with CYP1A1 genetic variants are more likely to have problems with acetylcholinesterase inhibition from glyphosate.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Psoriasis is an autoimmune condition that causes dry, sometimes itchy patches of skin. It is caused by the immune system attacking your skin cells, speeding up the turnover of the cells. Genetics plays a role in your susceptibility.
You brush, you floss, and your gums still bleed… perhaps you carry some of the genetic variants associated with gingivitis? Check your genetic data to see. (Member’s article)
Inflammation and breakdown of cartilage are at the root of osteoarthritis. Learn how your genes impact the pathways involved in arthritis.
Genetic variants can increase pancreatitis risk, along with other factors. Learn the causes of acute and chronic pancreatitis, plus how exocrine pancreatic insufficiency (EPI) drives nutrient deficiencies.
Are you considering a dental implant? Failure rates of dental implants are fairly low but still carry some risk. Genetic variants can influence the likelihood of long-term success.
Are you always tired even when you know you slept well? Discover more about the newest research on fatigue and how genetic susceptibility plays a part for some people.
Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.
Alopecia areata is an autoimmune-like disorder in which the immune system attacks the hair follicle. Learn about the triggers of alopecia areata, why the hair falls out, genetic variants that increase susceptibility, and possible treatment options.
L-theanine is known for reducing anxiety and promoting sleep. Discover the many benefits of l-theanine and how supplementation might work for you.
Learn about how genetic variants in certain inflammatory cytokines can increase or decrease the risk of recurrent miscarriage.
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
The PTPN22 gene plays a pivotal role in that balance, and genetic variants (SNPs) in PTPN22 increase your risk of autoimmune conditions such as vitiligo, alopecia, RA, type 1 diabetes, and autoimmune thyroid diseases. (Member’s article)
The TREM2 gene is important in how the brain’s immune system functions. Learn how variants in this gene impact the risk for Alzheimer’s disease.