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Estrogen metabolism, estrogen metabolites that increase cancer risk, estrogen genetic variants, steps to keep estrogen in balance

Estrogen: How It Is Made and How We Get Rid of It

Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.

Factor V Leiden (F5 Gene) variant, blood clot risk, deep vein thrombosis

Factor V Leiden Gene: Increased Risk of Blood Clots

The factor V Leiden genetic mutation significantly increases the lifetime risk of blood clots. Check your genetic data to see if you carry this mutation – and then learn to recognize the symptoms of blood clots.

Psoriasis Genes: How Genetics Point to Individualized Solutions

Psoriasis is an autoimmune condition that causes dry, sometimes itchy patches of skin. It is caused by the immune system attacking your skin cells, speeding up the turnover of the cells. Genetics plays a role in your susceptibility.

Dopamine receptors, natural Agonists and antagonist for dopamine

Dopamine Receptor SNPs: Addiction, Mood, ADHD, and Schizophrenia

Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.

How COMT gene variants affect pain sensitivity in fibromyalgia and chronic back pain

COMT in Pain Disorders

Genetic polymorphisms in COMT affect how we feel certain types of pain. These variants are linked to increased susceptibility to chronic pain disorders.

Diagram showing how COMT enzyme activity varies by genotype

COMT: How to Optimize Your Supplements for Your COMT Genotype

Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.

Vitamin B2: Riboflavin

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Vitamin B9: Active folate

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Essential Tremor: Causes and Possible Solutions

Essential Tremor: Causes and Possible Solutions

Essential tremor (ET) is a neurological disease causing involuntary shaking in places of the body while performing tasks such as writing or eating. Learn more about this disease and discover the genetic causes of ET.

Estrogen, Histamine, and Mast Cell Connections, genetic variants that affect histamine and mast cells, genetic variants that affect estrogen receptors

Estrogen, Histamine, and Mast Cell Connections

Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.

Luteolin: Anti-inflammatory Neuroprotective, Antihistamine, food high in luteolin, genetic

Luteolin: Antihistamine, Memory, and Brain Fog

New research suggests the benefits of luteolin (a flavonoid found in fruits, vegetables, and herbs) may include anti-inflammatory and neuroprotective properties.