DHFR and MTHFR: Folic Acid Metabolism
Methylfolate may be a better option than folic acid if you have certain genetic variants in the MTHFR or DHFR genes.
Search Results for: comt
Circadian Rhythm and Your Immune Response to Viruses
Your circadian rhythm influences your immune response. Learn how this rhythm controls white blood cell production and why melatonin protects against viral and bacterial infections.
HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
Will you go bald? Genetics and hair loss
What causes male pattern baldness? A combination of genetics, nutrition, and environmental toxins come together to form the risk factors for baldness. But genetics really seems to rule the roost here.
Hesperidin: An Anti-inflammatory and Immune Boosting Citrus Flavonoid
In a nutshell, the anti-inflammatory flavonoid found in citrus called hesperidin may help with cardiovascular health and preventing neuroinflammation. Learn more about this flavonoid found in citrus fruits.
MTHFR: Going Beyond C677T and A1298C
The MTHFR C677T and A1298C variants get a lot of press, but they do not give the whole picture of the MTHFR gene. Additional variants are impacting the functionality of the enzyme.
TNF-alpha: Inflammation, Chronic Diseases, and Genetic Susceptibility
Discover the role of TNF-alpha in inflammation and its link to chronic diseases. Learn how genetic variants affect TNF-alpha levels and explore natural solutions for chronic inflammation.
Quercetin: Scientific Studies + Genetic Connections
Quercetin is a natural flavonoid acting as both an antioxidant and anti-inflammatory. This article focuses on the results of clinical trials involving quercetin and links to specific genetic topics. Using your genetic data, you can make a more informed decision on whether quercetin is worth trying.
Small Fiber Neuropathy: Genetics, Causes, and Possible Solutions
Small Fiber Neuropathy (SFN) results in burning pain, numbness, odd sensations, or autonomic nervous system issues. Learn more about the possible causes and potential solutions to this debilitating disorder.
NQO1 Gene: Metabolism of Quinones, Benzene, and More
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article)
Genetics and Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
ITGB3: the PlA1/A2 variant and clotting
The PIA2 variant of the ITGB3 gene is linked to an increased risk of blood clots including stroke, heart attack, and DVT. But this variant also comes with a positive trade-off. Learn more with your genetic raw data.
Sulfotransferases: SULT Genes, Phase II Detoxification, and Sulfur
The SULT genes help with phase II detoxification of estrogens, neurotransmitters, certain carcinogens, and steroid hormones.
COMT Supplements Report
~ Clear Your Data ~ Understanding your data:If you have COMT rs4680 GG, you likely have faster (higher) COMT enzyme function.If you have COMT rs4680 AG, you likely have intermediate COMT enzyme function (highlighted in yellow).If you have COMT rs4680 AA, you likely have slow (lower) COMT enzyme function (highlighted … Read more
Familial Mediterranean Fever: Mimics fibromyalgia, arthritis, inflammation
Familial Mediterranean fever (FMF) is a genetic condition of inflammatory episodes that cause painful joints, pain in the abdomen, or pain in the chest. It is most often accompanied by a fever. FMF is often misdiagnosed as various pain-related conditions such as fibromyalgia, myofascial pain syndrome, or gouty arthritis.
Histamine, Mast Cell Activation, and Early Morning Insomnia
Histamine rising in the early morning hours may cause early waking insomnia. Mast cells and circadian rhythm disruption at the root.
Fisetin: Antioxidant and Senolytic
Fisetin is a natural flavonol found in several types of fruits and vegetables and may prove to be a critical anti-aging component. In several recent studies, fisetin clears out senescent cells holding a lot of promise for healthy aging. Learn more about the newest research into this possible longevity compound.
Longevity Genes: Hacking Healthspan Using Genomics
Several genes have been identified as longevity genes, linked to an increase in lifespan. Most importantly, these particular genetic variants show links to a longer ‘healthspan’. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.
Bryan Johnson’s Blueprint Protocol with Genetic Links
Overview of Bryan Johnson’s million dollar longevity protocol, with genetic insight to make it personalized and cheaper.
Which Type of Choline Works Best with Your Genes?
Choline is an often neglected nutrient essential to a healthy diet. Your genes are important in how much and which types of choline you need.
Obesity risk – GNB3 C825T
There are lots of different genetic variants that add a little bit to your risk of being overweight. Learn more about the GNB3 variants and obesity risk.
ME/CFS: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (and Long Covid?) Genes
Take a look into the science of the lingering effects of viruses, including chronic fatigue syndrome and long-haul viruses.
VMAT2 gene: The God Gene and Neurotransmitters
An examination of the current research for the ‘God gene’, explaining what it does and its importance in Parkinson’s disease.
Dads Matter: MTHFR Variants in Fathers Affect Miscarriage Risk
Dads matter – in conception, pregnancy, and throughout life. It is easy to see how prospective moms need to clean up their diets, exercise, and sleep well before getting pregnant, but recent studies show that a dad’s MTHFR variants also affect infertility and miscarriage risk.
Rosacea, Genetics, and Solutions
Rosacea is a chronic inflammatory skin condition that is driven by upregulated inflammation. Learn how your genes interact with environmental factors to cause rosacea.