Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.
Parkinson’s disease (PD) is not yet fully understood. Researchers think that it is caused by a combo of genetics and environmental factors. Learn more about this disease and the factors that lead to susceptibility.
Mast cells can be more easily triggered in the presence of high estrogen or estrogen-mimicking compounds. Histamine can also trigger mast cell degranulation. Together, this can cause a lot of symptoms related to mast cell activation.
Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you toward a Th2-dominant immune response, and variants increase the risk of allergies and asthma.
Several popular drugs, such as omeprazole, esomeprazole, and clopidogrel are metabolized by the CYP2C19 enzyme. There are important genetic variants in the CYP2C19 gene that changes how fast or slowly these drugs are broken down. Learn how these variants might affect their efficacy.
Do you know of someone with unexplained heart palpitations, spiking blood pressure, dizziness, and tinnitus? Discover how research is linking these symptoms to histamine, mast cells, and the spike protein.
Alopecia areata is an autoimmune-like disorder in which the immune system attacks the hair follicle. Learn about the triggers of alopecia areata, why the hair falls out, genetic variants that increase susceptibility, and possible treatment options.
The UGT family of enzymes is responsible for an important part of phase II detoxification. This article explains what the UGT enzymes do in the body, how your genes impact this part of detoxification, and lifestyle factors that can increase or decrease this detox process.
Quercetin is a natural flavonoid acting as both an antioxidant and anti-inflammatory. This article focuses on the results of clinical trials involving quercetin and links to specific genetic topics. Using your genetic data, you can make a more informed decision on whether quercetin is worth trying.
The CYP2C8 gene is important in the metabolism of several chemotherapy drugs as well as playing a role in the metabolism of NSAIDs. Genetic variants that alter how this enzyme works can impact your reaction to a medication.
Have you ever wondered why some people never seem to get the flu when it is going around? Simply put, some people are just more susceptible to getting the flu than others. Learn more and see if you are more or less susceptible to the flu.