TNF-alpha is a key inflammatory cytokine linked to autoimmune, cardiovascular, mood, and neurodegenerative diseases. Learn how TNF gene variants affect your risk and potential natural TNF inhibitors.
Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infections. Find out how genetic variants in this system increase your susceptibility to specific pathogens.
Genetic variants in immune, mitochondrial, and inflammatory pathways (NK cells, NLRP3, interferon, complement, TRP channels) increase ME/CFS susceptibility. Check your genes and explore research-backed solutions.
Explore how neuropilin variants shape neurodevelopment, vascular permeability, gut barrier function, viral entry (SARS‑CoV‑2, EBV, CMV), and risks for autoimmunity and cancer.
Explore the genetic basis of POTS, from HLA and norepinephrine transporter variants to EDS, MCAS, and long Covid connections, plus strategies to better manage symptoms.
Explore NLRP3 inflammasome genetics: How variants drive chronic inflammation in Alzheimer’s, diabetes, and autoimmune diseases. Discover triggers, health risks, and lifehacks like zinc & vitamin D to modulate it.
Find out your APOE type, understand your Alzheimer’s risk by genotype, sex, and ancestry, and learn about real prevention strategies.
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This can alter the gut microbiome – but protect against Norovirus infections.
While many people carry the HSV virus, only about 30% will get cold sores. Genetics is one reason.
Are you more genetically susceptible to the flu? Learn how your genes play a role and discover research-backed natural options to beat the flu.
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
Brain fog has many roots: nutrient deficiencies, hypoxia, inflammation, viral infections, microclots, histamine, amino acid metabolism, and genetics — plus targeted strategies to restore clear thinking.
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Long Covid is the persistence of symptoms after having COVID-19. Learn more about the underlying causes and treatments backed by the newest research.
There have been several interesting studies linking obesity to a viral infection, specifically an adenovirus. Learn more about this virus and its association with obesity.
Explore the research-backed strategies for preventing or managing respiratory illnesses. Don’t let a cold get you down this year.
The interesting thing about Lyme disease is that the genetic variants you carry impact both how the disease affects you and how well antibiotics work for you. Learn whether your genetic variants are linked to post-treatment Lyme disease symptoms such as joint pain. (Member’s article)
Genetic variants can increase pancreatitis risk, along with other factors. Learn the causes of acute and chronic pancreatitis, plus how exocrine pancreatic insufficiency (EPI) drives nutrient deficiencies.
The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome. Learn how this opioid antagonist works on the immune system and how your genetics can play a part in its efficacy.
The PlA2 variant of the ITGB3 gene is linked to an increased risk of blood clots including stroke, heart attack, and DVT. But this variant also comes with a positive trade-off with reduced risk of hantavirus infection severity.
The APOBEC3 family of enzymes has a unique way of stopping viruses from replicating. Your genes can affect whether the virus becomes inactive or more virulent.
The CCR5 gene is an important player in the immune response. The CCR5-delta32 variant can reduce susceptibility to certain HIV strains, particularly in people with two copies.