Parkinson’s Disease Risk: Genetics, Environmental Exposures, and Prevention Strategies
Parkinson’s: Explore key genes, environmental risks, gut microbiome factors, and research‑based lifehacks that may help protect dopaminergic neurons.
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Brain Fog: Causes, genetics, and individualized solutions
Brain fog has many roots: nutrient deficiencies, hypoxia, inflammation, viral infections, microclots, histamine, amino acid metabolism, and genetics — plus targeted strategies to restore clear thinking.
Schizophrenia: Genetic and Environmental Factors
Schizophrenia is a complex disease caused by a combination of genetic susceptibility along with environmental factors. Research points to multiple pathways involved in schizophrenia and schizoaffective disorder.
Tryptophan Pathways: Kynurenine, Serotonin, and Melatonin
Genetic variants in tryptophan pathway enzymes alter quinolinic and kynurenic acids, NAD+ production, and serotonin synthesis. These genes influence mood, sleep, fatigue, immunity, and ong Covid brain fog risk.
Highly Sensitive People: Genes, Brain Function, and Sensory Sensitivity
Genetic variants are linked to being a Highly Sensitive Person – feeling more deeply and more sensitive to environmental stimuli.
Rosacea, Genetics, and Solutions
Rosacea is a chronic inflammatory skin condition that is driven by upregulated inflammation. Learn how your genes interact with environmental factors to cause rosacea.
Dopamine Synthesis SNPs: Genes, lifestyle, diet, and dopamine optimization
Genetic variants in dopamine synthesis and breakdown genes interact with circadian rhythm, gut microbes, nutrients, and toxins, shaping risks for procrastination, psychosis, hypertension, Parkinson’s, and addiction.
Creatine: Boosting Muscles and Increasing Brain Power
Creatine is an amino acid used in muscle tissue and the brain for energy in times of stress. Genes play a role in creatine synthesis. Find out what the research shows about creatine supplements for muscle mass and cognitive function.
Sulfotransferases: SULT Genes, Phase II Detoxification, and Sulfur
The SULT genes help with phase II detoxification of estrogens, neurotransmitters, certain carcinogens, and steroid hormones.
Estrogen: How It Is Made and How We Get Rid of It
Estrogen – from how much is made to how it is broken down – is dependent on both genetics and lifestyle factors and affects both men and women. This article explains how estrogen is made, how it is eliminated from the body, which genes are involved, and how this influences the risk of breast cancer, prostate cancer, and fibroids.
Phase I and Phase II Detoxification Pathways Explained
Key takeaways: The body eliminates harmful substances through a three-phase process. Phase I detoxification generally involves the CYP450 enzymes, which break down substances to make them more polar. This phase often produces reactive or toxic metabolites. Phase II takes the reactive metabolites from phase II and adds another molecule to … Read more
Histamine, Mast Cell Activation, and Early Morning Insomnia
Histamine rising in the early morning hours may cause early waking insomnia. Mast cells and circadian rhythm disruption at the root.
Adenoviruses: Causing Weight Gain and Obesity
There have been several interesting studies linking obesity to a viral infection, specifically an adenovirus. Learn more about this virus and its association with obesity.
Avoiding Getting Sick: Research-backed Ways to Prevent Covid, Colds, and Flu
Explore the research-backed strategies for preventing or managing respiratory illnesses. Don’t let a cold get you down this year.
Bryan Johnson’s Blueprint Protocol with Genetic Links
Overview of Bryan Johnson’s million dollar longevity protocol, with genetic insight to make it personalized and cheaper.
Dopamine Receptor SNPs: Addiction, Mood, ADHD, and Schizophrenia
Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.
CoQ10: Genes, Benefits, and Mitochondrial Energy
CoQ10, or ubiquinone, is an integral part of mitochondrial energy production. It is also used as a lipid-soluble antioxidant. Learn how age and genes affect it.
Hot flashes in menopause: Genetics and natural solutions
Hot flashes affect up to 80% of women going through menopause. Genetics, environment, and diet can make them worse. Target the right solutions.
Low-Dose Naltrexone: LDN & Genetics
The use of low dose naltrexone (LDN) can be an effective treatment for some autoimmune diseases, pain syndromes, and chronic fatigue syndrome. Learn how this opioid antagonist works on the immune system and how your genetics can play a part in its efficacy.
Riboflavin (Vitamin B2), MTHFR, and Deficiency Symptoms
Learn how riboflavin (vitamin B2) affects MTHFR genes, methylation, and energy. Find out the deficiency symptoms, food sources, dosage, and whether you need more based on your genetics.
Nickel Allergy: Genetics, causes, natural solutions
Nickel allergy: Explore how genes, everyday exposures, and diet contribute to nickel sensitivity, including rashes, GI symptoms, and brain fog.
Fatigue: Root Causes, Genetics, Personalized Solutions
Are you always tired even when you know you slept well? Discover more about the newest research on fatigue and how genetic susceptibility plays a part for some people.
Vitamin B12: Methylation cycle and more
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Folate Optimization: MTHFR and Fertility
MTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.
Vitamin B9: Active folate
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