Join Here   |   Log In

NQO1 Gene: Metabolism of quinones, benzene, and more

The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article)

Psychopaths: Born not made?

Can you be born a psychopath? Are there genes linked to psychopathy? Discover how your genes don’t predestine you to become a psychopath.

Longevity Genes: Hacking healthspan using genomics

Several genes have been identified as longevity genes, linked to an increase in lifespan. Most importantly, these particular genetic variants show links to a longer ‘healthspan’. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.

Dirty Genes Protocol

Do your genes really get ‘dirty’? The quick answer is no but discover the meaning of this concept and how to better relate it to your genes.

Research Studies on Plant Compounds for SARS-CoV-2

This article explains the current research (August 2021) on natural compounds that may help to combat SARS-CoV-2. Included are clinical trial results on nigella sativa, curcumin, and quercetin.

CBS Gene Variants and Low Sulfur Diet

Some clinicians recommend a low sulfur diet for people with CBS mutations. Find out what the research shows – and why that recommendation is not backed up. (Member’s article)

MTHFR: Going Beyond C677T and A1298C

The MTHFR C677T and A1298C variants get a lot of press, but they do not give the whole picture of the MTHFR gene. Additional variants are impacting the functionality of the enzyme.

MTHFR, depression, anxiety, symptoms and treatment

We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.

Vaccines and the MTHFR mutation

A lot of people use the MTHFR variants as a reason not to vaccinate their kids. Is there any science to back this up? See what the research says.

FUT2: How to check if you are a secretor or non-secretor?

A genetic variant in the FUT2 gene controls whether or not you secrete your blood type into your saliva and other bodily fluids, such as your intestinal mucosa. This alters the gut microbiome – and protects you from Norovirus.

how to check your 23andMe data for MTHFR mutation

MTHFR: How to check your data for C677T and A1298C

Key takeaways: ~ The MTHFR gene impacts how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. ~ Genetic variants can impact how well this gene works. ~ Optimizing diet and supplements related to methylation may impact several aspects of wellness. Check your raw data for C677T, A1298C, and more This article shows you what to check in your raw data, then explains the scientific research on the MTHFR variants. At the end of the article, you will find solid, evidence-based lifestyle solutions for optimizing the MTHFR variants. Frankly, there is a lot of misinformation on the internet about the MTHFR gene mutations, so I will explain the peer-reviewed research studies here. I’ll clearly explain how to optimize your diet (or add in supplements) if you carry MTHFR genetic variants. MTHFR Gene Mutations Genotype Report: Let’s put the rest of this article into context by checking your two more common MTHFR variants first. (I’ll include other MTHFR variants later in the article). You don’t need to do specific genetic testing or buy health … Read more

Asprin, Heart Disease Prevention, and Genetics

While large population studies show the benefits of aspirin, research shows that these heart-health benefits are dependent on your genes. Find out more and check your genetic raw data.

Detoxification: Phase I and Phase II Metabolism

Key takeaways: ~ Phase I and phase II detoxification are the primary ways your body eliminates toxins. ~ Genetic variants in these pathways affect how well you detoxify certain substances. Detoxification and Genetic Pathways: Your body is remarkably capable of ridding itself of harmful substances through complex detoxification pathways. In today’s world, we are all exposed to various toxicants (manufactured toxins) through pesticide residue, air pollution, skin care products, and medications. Additionally, our bodies break down and eliminate substances made and used within ourselves, as well as natural plant compounds. All of these processes rely on intricate systems in our bodies that metabolize and eliminate toxins. Many people have genetic variants that impact how medications and toxicants are broken down and eliminated. Our genes make us unique, and one difference between people is seen in the differences in the phase I and phase II detoxification pathway genes. Understanding where you have a genetic sensitivity — and then optimizing to avoid specific toxicants or drugs — is the key here. To better understand this process, let’s first explore how phase I … Read more

Genetic Lifehacks: Understand your genetic data

Latest Articles and Genotype Reports: Inflammation and Immune Response More articles in Inflammation and Immune >>> Mood and Brain Genes >>>More in Mood and Brain >>> Methylation Cycle Genes More in Methylation Cycle >>> Sleep and Circadian Rhythm Genes More in Sleep & Circadian Rhythm >>> Detoxification & Medications More in Detoxification >>> Disease Prevention: Genetic Guides More in Disease Prevention >>> Heart Health: Genetic Guides >>>More in Heart Health >>> Longevity Genes and Health Aging >>>More in Longevity>>> My book just launched! Get your copy of Histamine Lifehacks today. Mitochondrial Health & Genes >>> More in Mitochondrial Health >>> Explore by Symptoms, Supplements, Diet, or Pathway: Hormones & Your Genes More in Hormones >>> Metabolic Health Genes More in Metabolic Health >>> Vitamins and Foods: Nutrigenomics >>> More in Vitamins and Foods >>> Traits: Genetic Guides More in Traits >>> Fertility & Pregnancy More in Fertility >>> Supplements & Genes >>>More in Supplement Research >>> Autoimmune Disease Genes More articles in Autoimmune >>> My Story… Hi! I’m Debbie Moon. Welcome to Genetic Lifehacks. When I first had my genetic … Read more

Fisetin: Antioxidant and Senolytic

Fisetin is a natural flavonol found in several types of fruits and vegetables and may prove to be a critical anti-aging component. In several recent studies, fisetin clears out senescent cells holding a lot of promise for healthy aging. Learn more about the newest research into this possible longevity compound.

Genetics and Seasonal Affective Disorder

Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.

Histamine Intolerance, MTHFR, and the Methylation Cycle

Genetics plays a role in how well your body breaks down histamine. Histamine that is out of balance with the body’s ability to break it down can cause symptoms that are collectively known as histamine intolerance. Discover how to check your genes that are involved with histamine levels.

Dopamine Fasting: Addicted to the internet?

Genetics plays a role in susceptibility to addictive behavior, including internet and smartphone addiction. This article examines the latest fad of dopamine fasting along with genetic variants tied to internet use problems, smartphone usage disorder, and gaming disorders.

Dopamine Receptor SNPs: Addiction, Mood, ADHD, and Schizophrenia

Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.