Gallstone Genes
The genetic link to gallstones centers around the genes involved in regulating the absorption of cholesterol from plants and the excretion of cholesterol from the body. Learn more about the genetic variants that increase your risk.
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Red Hair and the MC1R Gene
To have red hair, you need to carry two variants in the MC1R gene. We all know our hair color, but it turns out that if you carry one MC1R genetic variant (and don’t have red hair) you are still at an increased risk for skin cancer.
CYP17A1: Steroid Hormone Production (Testosterone, Estrogen, and DHEA)
CYP17A1 is important in the production of steroid hormones including testosterone and estrogen. SNPs in CYP17A1 impact hormone levels.
CYP1A2 Gene: Fast or Slow Caffeine Metabolizer?
The CYP1A2 gene breaks down caffeine, several major prescription drugs, and interacts with smoking. Learn how your genes influence caffeine metabolism and more.
Alpha-1 Antitrypsin Deficiency: Genetic Raw Data, Carrier Effects, Interactions with TNF
A genetic mutation in the SERPINA1 gene causes alpha-1 antitrypsin deficiency. This increases a person’s susceptibility to COPD (chronic obstructive pulmonary disease) and, in some cases, cirrhosis of the liver. Knowing that you carry this mutation can be a great incentive to avoid smoking and to be kind to your liver.
Vitamin K: Bone Strength, Blood Clots, Calcification, and Genetics
Genetic variations cause people to have higher or lower levels of vitamin K, which can affect blood clotting. Learn more about the genes that affect vitamin K and how it relates to your genetic raw data.
Progesterone: creation, receptors, effects, and metabolism
Progesterone is an important hormone in women’s health. Find out how your body reacts to progesterone, breaks it down for elimination, and discover lifehacks to adjust the levels.
Alpha-Ketoglutarate: A Key to Healthspan and Fighting Age-Related Diseases
Supplementing with Alpha-ketoglutarate (αKG) might be beneficial for longevity since it plays a role in energy production and inflammation reduction.
Are Cold Sores Genetic? Who gets them and why
While many people carry the HSV virus, only about 30% will get cold sores. Genetics is one reason.
Small Fiber Neuropathy: Genetics, Causes, and Possible Solutions
Small Fiber Neuropathy (SFN) results in burning pain, numbness, odd sensations, or autonomic nervous system issues. Learn more about the possible causes and potential solutions to this debilitating disorder.
Irritable Bowel Syndrome (IBS): Targeted Solutions Based on Your Genes
There are multiple causes of irritable bowel syndrome (IBS), and genetics can definitely play a role in IBS symptoms. Pinpointing your genetic cause may help you to figure out the right solution for you. (Member’s article)
Psoriasis Genes: How Genetics Point to Individualized Solutions
Psoriasis is an autoimmune condition that causes dry, sometimes itchy patches of skin. It is caused by the immune system attacking your skin cells, speeding up the turnover of the cells. Genetics plays a role in your susceptibility.
MRGPRX2: Mast Cells, Itching, & Drug Hypersensitivity Reactions, Including Fluoroquinolones
MRGPRX2 is a recently discovered mast cell receptor. It is linked to drug hypersensitivity reactions as well as asthma, rosacea, and IBD.
The Genetics Behind Gray Hair: Causes, Factors, and Natural Solutions
Do our genes or environment influence how our hair grays as we age? Discover the science behind graying hair and what (if anything) can be done about it.
Sudden Hearing Loss: Viruses, Vaccines, and Genes
Genetic variants can significantly increase your risk of sudden sensorineural hearing loss. Learn more about the current research on sudden sensorineural hearing loss, including links to viral and vaccine causes.
NQO1 Gene: Metabolism of Quinones, Benzene, and More
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article)
CYP2D6: Medication Interactions, Natural Inhibitors, and Anxiety Traits
The CYP2D6 enzyme is responsible for metabolizing about 25% of commonly used medications. There are several fairly common genetic variants in CYP2D6 that affect how quickly you will break down a drug.
Cancer Prevention Strategies for Lynch Syndrome Mutations
Lynch Syndrome increases the risk of certain cancers. The cause relates to inherited mutations in the genes responsible for stopping the replication of cancerous cells. Learn how cancer occurs, risks involved with this particular syndrome, and prevention strategies to implement for risk reduction
Age-Related Macular Degeneration Genes
Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly. You will find supplements specifically promoted for preventing AMD. This article explains age-related macular degeneration, delves into the genetic risks, and then explains which supplements are likely to be protective and which may do more harm than good.
Nitric Oxide Synthase (NOS3): Heart Health, Blood Pressure, and Healthy Aging
Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.
Back Pain: Genetics, Root Causes, and Solutions
For some people, back pain is a daily occurrence that drastically affects their quality of life. For others, it may be an intermittent nagging problem, often without rhyme or reason. Your genes play a role in whether disc degeneration gives you back pain.
Why Light at Night Increases Cancer Risk
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
Skin Cancer: Genetics and Prevention
Skin cancer is the most common form of cancer and many forms are highly treatable if caught early. Learn more about the different types of skin cancer, your genetic risks, and lifestyle changes to help reduce risk.
Antibiotics: Genetics and Antibiotic Reactions
Genetics plays a role in the susceptibility to antibiotic allergies. Learn which genetic variants increase your risk.
Prions: Genetic Mutations that Increase Prion Disease Risk
Prions are able to infect, causing the normal protein around them to also misfold. These misfolded proteins aggregate to cause neurogenerative disease. Susceptibility to prion diseases depends in part on your genes.