Pyruvate Dehydrogenase is central to cellular energy production. Learn about its role in energy production, genetic mutations, association with ME/CFS and Long Covid, and strategies to manage its deficiencies.
Is there an easy way to compare what diet might be best based on your genotype? Research shows some interesting associations between genotype and diet interactions and weight loss.
Explore brain fog in detail, looking at the physiological causes, genetic susceptibility, and personalized solutions.
Your genes play a role in your susceptibility to migraines. Find out what is going on when you have a migraine and solutions that fit your genes.
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.
Not all type 2 diabetes risk is from what you eat… Genetics plays a big role in diabetes. Learn more about your genetic susceptibility.
For some people, genetic variants can cause HbA1c levels not to accurately reflect their average blood glucose levels. Find out how your genes impact A1c readings.
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.
GABA (gamma-Aminobuyteric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions, including anxiety and PTSD.
Non-alcoholic fatty liver disease (NAFLD) can be caused by genetic susceptibility, diet, and lifestyle factors. The good news is that fatty liver disease is reversible.
Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.
Several genes have been identified as longevity genes, linked to an increase in lifespan. Most importantly, these particular genetic variants show links to a longer ‘healthspan’. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.
The FTO gene is nick-named the ‘fatso gene’ because of its association with obesity. This article digs into the current research on the FTO gene and then will give you some science-based options for controlling your weight if you carry the FTO genetic variant.
Explore the complexities of PCOS, including symptoms, hormonal dysregulation, and the role of genetics. Learn how to target individual pathways.
There are multiple causes of irritable bowel syndrome (IBS), and genetics can definitely play a role in IBS symptoms. Pinpointing your genetic cause may help you to figure out the right solution for you. (Member’s article)
Take a look into the science of the lingering effects of viruses, including chronic fatigue syndrome and long-haul viruses.
Our ancient ancestors lived much differently than we do today. They were hunter-gatherers, living off of fish, meat, and plant foods that they gathered. A huge shift took place when those hunter-gatherers began farming, growing grains, and storing them so that there would be food available all year. Learn if you carry the hunter-gatherer or farmer gene variant. (Member’s article)
If you have tried fasting or perhaps a ketogenic diet and felt horrible, there could be a genetic reason. You might carry a genetic mutation that causes SCADD (short-chain acyl-CoA dehydrogenase deficiency).
Intermittent fasting and ketosis have a lot of benefits, but they may not be right for you. Your genes play a role in how you feel when fasting.
HDL cholesterol levels are considered to be about half due to genes with the rest due to diet, infection, etc. Learn more about the genetic variants that influence HDL cholesterol and how it affects heart health.
Brain-derived neurotrophic factor (BDNF) is a fascinating growth hormone that performs many functions in our brain. Its involvement helps to support neurons and neuronal growth. In addition, it plays a role in long-term memory — and it also is important in obesity.
The body’s circadian clock regulates many different functions over the course of a 24-hour day. The genes that code for different parts of the circadian clock have a wide-ranging effect on sleep, mood, and overall health.