Circadian clock gene variants in CLOCK, BMAL1, PER, CRY, NPAS2, and OPN4 interact with light exposure to disrupt hormones, sleep, and mood, increasing risk for depression, anxiety, and seasonal affective disorder.
VMAT2, the so‑called “God gene,” packages dopamine, serotonin, and other monoamines into vesicles, protecting neurons from oxidative stress and influencing risks for Parkinson’s, PTSD, alcohol dependence, and diabetes.
Mycotoxins from food and water-damaged buildings are cleared via CYP450, GST, and UGT pathways. Variants in these detox genes explain why mold and mycotoxin sensitivity varies.
Find out your APOE type, understand your Alzheimer’s risk by genotype, sex, and ancestry, and learn about real prevention strategies.
Overview how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes.
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction.
Discover how genetics, triggers, and personalized strategies shape migraine prevention and relief. Find actionable solutions based on your DNA.
Non-alcoholic fatty liver disease (NAFLD) can be caused by genetic susceptibility, diet, and lifestyle factors. The good news is that fatty liver disease is reversible.
Genetic variants play a role in susceptibility to obsessive-compulsive disorder. Understanding your genes may help you understand OCD better and help you to target the right treatment.
Brain fog has many roots: nutrient deficiencies, hypoxia, inflammation, viral infections, microclots, histamine, amino acid metabolism, and genetics — plus targeted strategies to restore clear thinking.
Genetic variants in tryptophan pathway enzymes alter quinolinic and kynurenic acids, NAD+ production, and serotonin synthesis. These genes influence mood, sleep, fatigue, immunity, and ong Covid brain fog risk.
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
Your vitamin D levels are impacted by sun exposure and your genes. Learn more about how vitamin D is made in the body and how your genetic variants impact your levels.
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
Not all type 2 diabetes risk is from what you eat… Genetics plays a big role in diabetes. Learn more about your genetic susceptibility.
Genetic variants that increase inflammation also increase the risk of pancreatitis. Learn about causes and natural solutions for pancreas problems.
Partial IgA deficiency, which affects up to 1% of the population, can have a genetic component and overlaps with some autoimmune diseases.
Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.
Are you considering a dental implant? Failure rates of dental implants are fairly low but still carry some risk. Genetic variants can influence the likelihood of long-term success.
How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.
Trying to get pregnant? Healthy eggs are vital for a successful pregnancy. Discover four key ways to improve your egg quality, according to research studies.
Genetics plays a significant role in your blood glucose regulation. Discover your genetic susceptibility to blood sugar problems to help with blood glucose stability.
MS susceptibility is linked to both genetic causes and environmental factors. Learn how those two combine – and possible solutions.
Hundreds of identified genes influence intelligence, from IQ scores to musical ability. Learn more about your intelligence strengths and ways to enhance your cognitive function.