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How mast cells release histamine and other mediators in mast cell activation syndrome, and the genetics that influence MCAS

Mast Cells: MCAS, Genetics, and Solutions

Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.

Genetic variants that cause Hemochromatosis, symptoms of Hemochromatosis

Building Up Iron: Hemochromatosis Mutations

A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.

Celiac Disease: Genes, Symptoms and HLA type

Celiac Genes: How to Check Your Raw Data

Celiac disease is caused by a combination of environmental factors (eating gluten, other factors) and having the genetic variants that cause susceptibility to the disease. Without the genetic susceptibility, you won’t have celiac.

HPA Axis disfunction, ways to reduce cortisol levels, genetic variants related to HPA Axis disfunction.

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

Why Lyme disease becomes chronic for some people and the gene variants involved

Chronic Lyme: Genetic Susceptibility

The interesting thing about Lyme disease is that the genetic variants you carry impact both how the disease affects you and how well antibiotics work for you. Learn whether your genetic variants are linked to post-treatment Lyme disease symptoms such as joint pain. (Member’s article)

Sjogren’s Syndrome: Causes, Genes, Solutions, symptoms

Sjogren’s: Causes, Genes, Solutions

Are you dealing with dry eyes and dry mouth? Sjögren’s syndrome is an autoimmune disorder that affects moisture-producing glands. Discover the underlying causes of Sjögren’s syndrome and the genetic variants that increase susceptibility.

Covid-19: Long Covid and Long Spike

Long Spike

Discover the research and genetic links to why you may be more susceptible to certain outcomes with long spike.

Genes that Impact Ferritin Levels

Genes that Impact Ferritin Levels

Ferritin is the storage protein for iron in the body. Storing too little or too much iron can be an indicator of an underlying problem. Discover the genetic variants that impact ferritin and how to increase ferritin with supplements or foods.

G6PD Deficiency: How to Check Your Genes

How to Check Your Genetic Data for G6PD Deficiency

People who carry the genetic mutations that cause G6PD deficiency are at an increased risk for hemolytic anemia when taking quinine-based medications. This article is intended to be a ‘heads up’ for anyone who is considering using quinine or chloroquine without a doctor’s advice for COVID-19.

Hypertension Risk Factor: CYP11B2 Variant

Hypertension Risk Factor: CYP11B2 Variant

Hypertension risk can be modifiable in terms of diet and exercise however genetics can play a part in risk. Learn more about how the CYP11B2 variant can increase the risk of hypertension.